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Articles Published Processes
11/14/2025 8:23:14 AM | Browse: 30 | Download: 60
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Received |
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2025-06-30 01:12 |
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Peer-Review Started |
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2025-07-01 08:37 |
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First Decision by Editorial Office Director |
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2025-07-15 07:50 |
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Return for Revision |
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2025-07-15 07:50 |
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Revised |
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2025-07-28 22:06 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-09-08 06:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-09-26 07:51 |
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Articles in Press |
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2025-09-26 07:51 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-07 05:44 |
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Publish the Manuscript Online |
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2025-11-14 08:23 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Review |
| Article Title |
Crosstalk between oxidative stress and inflammatory pathways: Natural therapeutic approaches for diabetic wound healing
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yan-Ling Guo, Wen-Jing Niu, Hao-Ran Jiao, Yun-Ping Li, Chuan Xu, Xin Zhou and Jun Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81973854 |
| Scientific Research Programme Project of Hebei Provincial Administration of Traditional Chinese Medicine |
T2025095 |
| The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine ‘TuoXin Project’ Fund Scientific Research Topics |
2023012 |
| Key Project of the Huzhou City Science and Technology Plan |
2023GZ83 |
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| Corresponding Author |
Jun Wang, MD, Professor, Department of Wound and Vascular Surgery, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture Moxibustion, No. 88 Changling Road, Xiqing District, Tianjin 300381, China. tjzywangjun@126.com |
| Key Words |
Diabetic wound healing; Oxidative stress; Inflammation; Natural medicines; Signaling pathways |
| Core Tip |
Oxidative stress and inflammation significantly impede wound healing in diabetes through a complex interactive mechanism. Natural therapeutic agents, including polyphenols, flavonoids, and terpenoids, have shown promise in mitigating oxidative damage and inflammatory responses and promoting angiogenesis, collagen deposition, and fibroblast function. This review highlights the intricate crosstalk between oxidative stress and inflammatory pathways in diabetic wound healing and underscores the potential of natural products as adjunctive therapies, emphasizing the need for further clinical validation to establish their efficacy and safety. |
| Publish Date |
2025-11-14 08:23 |
| Citation |
Guo YL, Niu WJ, Jiao HR, Li YP, Xu C, Zhou X, Wang J. Crosstalk between oxidative stress and inflammatory pathways: Natural therapeutic approaches for diabetic wound healing. World J Diabetes 2025; 16(11): 111400 |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i11/111400.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i11.111400 |
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