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Articles Published Processes
10/27/2025 8:08:12 AM | Browse: 69 | Download: 47
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Received |
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2025-06-30 07:50 |
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Peer-Review Started |
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2025-06-30 07:50 |
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To Make the First Decision |
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Return for Revision |
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2025-07-23 09:14 |
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Revised |
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2025-08-05 17:27 |
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Second Decision |
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2025-09-02 02:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-09-02 03:27 |
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Articles in Press |
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2025-09-02 03:27 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-09-20 04:38 |
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Typeset the Manuscript |
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2025-10-21 01:47 |
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Publish the Manuscript Online |
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2025-10-27 08:08 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Microbiome and gut-liver interactions: From mechanisms to therapies
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Muhammad Aarish Anis, Yumna Shahid, Ammara A Majeed and Shahab Abid |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Shahab Abid, Professor, Section of Gastroenterology, Department of Medicine, Aga Khan University, Stadium Road, P O Box 3500, Karachi 74800, Sindh, Pakistan. shahab.abid@aku.edu |
| Key Words |
Microbiome; Hepatic encephalopathy; Steatotic liver disease; Fecal microbiota transplantation; Cholangiopathies |
| Core Tip |
The gut-liver axis is emerging as a key player in the pathogenesis and treatment of chronic liver diseases. From alcoholic hepatitis to cholangiopathies like primary biliary cholangitis and primary sclerosing cholangitis, disruptions in the gut microbiota fuel liver inflammation, fibrosis, and immune dysregulation. This review explores how targeting the microbiome through fecal microbiota transplantation, bile acid modulators, and precision medicine can transform liver disease management. With growing evidence supporting microbiome-based interventions, this article offers a compelling look into how restoring gut-liver harmony may shift treatment from symptom control to disease reversal unlocking the future of personalized hepatology. |
| Publish Date |
2025-10-27 08:08 |
| Citation |
<p>Anis MA, Shahid Y, Majeed AA, Abid S. Microbiome and gut-liver interactions: From mechanisms to therapies. <i>World J Gastroenterol</i> 2025; 31(40): 111409</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i40/111409.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i40.111409 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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