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Articles Published Processes
11/21/2025 7:06:12 AM | Browse: 97 | Download: 272
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Received |
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2025-06-30 04:55 |
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Peer-Review Started |
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2025-06-30 04:55 |
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First Decision by Editorial Office Director |
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2025-07-07 01:41 |
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Return for Revision |
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2025-07-08 13:41 |
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Revised |
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2025-07-20 12:41 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-17 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-17 10:43 |
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Articles in Press |
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2025-10-17 10:43 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-14 02:11 |
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Publish the Manuscript Online |
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2025-11-21 07:06 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Role of the gut microbiome in the development and prognosis of pediatric leukemia
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jelena Roganovic, Mia Radosevic and Ana Dordevic |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jelena Roganovic, MD, PhD, Tenured Professor, Department for Pediatric Oncology and Hematology, Children's Hospital Zagreb, Klaiceva 16, Zagreb 10000, Croatia. jelena.roganovic02@gmail.com |
| Key Words |
Pediatric leukemia; Gut microbiome; Dysbiosis; Immune modulation; Microbiome-based therapy; Prognosis |
| Core Tip |
The gut microbiome plays a pivotal role in the development, prognosis, and management of pediatric leukemias. This mini-review synthesizes current evidence on microbial dysbiosis as both a risk factor and prognostic biomarker, discusses methodological and safety challenges relating to gut microbiome research, and reviews innovative gut microbiome-targeted therapies. By advocating for pediatric-specific safety frameworks and integrating gut microbiome profiling into clinical protocols, this paper underscores the gut microbiome’s potential to transform early detection, personalized therapy, and long-term outcomes in pediatric leukemia. |
| Publish Date |
2025-11-21 07:06 |
| Citation |
Roganovic J, Radosevic M, Dordevic A. Role of the gut microbiome in the development and prognosis of pediatric leukemia. World J Clin Oncol 2025; 16(11): 111419 |
| URL |
https://www.wjgnet.com/2218-4333/full/v16/i11/111419.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v16.i11.111419 |
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