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12/22/2025 7:43:00 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastrointestinal Pathophysiology
Manuscript ID 111432
Country Brazil
Received
2025-06-30 05:34
Peer-Review Started
2025-06-30 05:36
First Decision by Editorial Office Director
2025-07-11 10:22
Return for Revision
2025-07-14 02:16
Revised
2025-07-26 17:03
Publication Fee Transferred
Second Decision by Editor
2025-10-27 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-27 08:59
Articles in Press
2025-10-27 08:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-28 01:35
Publish the Manuscript Online
2025-12-22 07:43
ISSN 2150-5330 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Update on the pathogenesis and clinical management of Helicobacter pylori gastric infection and associated diseases
Manuscript Source Invited Manuscript
All Author List Juan Marcos Caram Costa, Carlos Eduardo Oliveira Aguiar, Marina Maria Gomes Leite Oliveira, Victoria Cenci Dietrich, Pedro Henrique Melo Lima, João Pedro Camargo Freire, Fabian Fellipe Bueno Lemos, Dulciene Maria de Magalhães Queiroz and Fabrício Freire de Melo
ORCID
Author(s) ORCID Number
Juan Marcos Caram Costa http://orcid.org/0009-0003-4045-9684
Carlos Eduardo Oliveira Aguiar http://orcid.org/0009-0000-7108-0640
Marina Maria Gomes Leite Oliveira http://orcid.org/0009-0000-5785-438X
Victoria Cenci Dietrich http://orcid.org/0009-0007-3627-6454
Pedro Henrique Melo Lima http://orcid.org/0009-0006-1206-9883
João Pedro Camargo Freire http://orcid.org/0009-0007-0384-4224
Fabian Fellipe Bueno Lemos http://orcid.org/0000-0002-4686-7086
Dulciene Maria de Magalhães Queiroz http://orcid.org/0000-0003-1334-9423
Fabrício Freire de Melo http://orcid.org/0000-0002-5680-2753
Funding Agency and Grant Number
Corresponding Author Fabrício Freire de Melo, PhD, Professor, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Rua Hormindo Barros, 58, Quadra 17, Lote 58, Vitória da Conquista 45029-094, Bahia, Brazil. freiremeloufba@gmail.com
Key Words Helicobacter pylori; Virulence factors; Immunological response; Tailored therapy; Treatment adjuvants
Core Tip Helicobacter pylori (H. pylori) is a gastric pathogen that infects more than 40% of the world’s population. Pathophysiological mechanisms of infection and evolution to severe diseases range from host’s immunological responses and virulence factors, which are intricately regulated. Diagnosis and treatment strategies have been evolving in order to overcome the burden of antibiotic resistance and the need for invasive procedures. This article aims to provide an overview of H. pylori infection, highlighting important advances in the understanding of pathogenesis and new insights for effective clinical management.
Publish Date 2025-12-22 07:43
Citation

Costa JMC, Aguiar CEO, Oliveira MMGL, Cenci Dietrich V, Lima PHM, Freire JPC, Lemos FFB, Queiroz DMM, de Melo FF. Update on the pathogenesis and clinical management of Helicobacter pylori gastric infection and associated diseases. World J Gastrointest Pathophysiol 2025; 16(4): 111432

URL https://www.wjgnet.com/2150-5330/full/v16/i4/111432.htm
DOI https://dx.doi.org/10.4291/wjgp.v16.i4.111432
Full Article (PDF) WJGP-16-111432-with-cover.pdf
Manuscript File 111432_Auto_Edited_022344.docx
Answering Reviewers 111432-answering-reviewers.pdf
Audio Core Tip 111432-audio.m4a
Conflict-of-Interest Disclosure Form 111432-conflict-of-interest-statement.pdf
Copyright License Agreement 111432-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 111432-non-native-speakers.pdf
Peer-review Report 111432-peer-reviews.pdf
Scientific Misconduct Check 111432-scientific-misconduct-check.png
Scientific Editor Work List 111432-scientific-editor-work-list.pdf
CrossCheck Report 111432-crosscheck-report.pdf