12/5/2025 6:43:30 AM | Browse: 15 | Download: 36
| Publication Name | World Journal of Clinical Cases |
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| Manuscript ID | 111438 |
| Country | Japan |
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| ISSN | 2307-8960 (online) |
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| Open Access | This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright | © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Infectious Diseases | ||||
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| Manuscript Type | Case Report | ||||
| Article Title | Recurrence of acyclovir-resistant herpes encephalitis in an immunocompromised patient: A case report | ||||
| Manuscript Source | Invited Manuscript | ||||
| All Author List | Daisuke Usuda, Daiki Furukawa, Rikako Imaizumi, Rikuo Ono, Yuki Kaneoka, Eri Nakajima, Masashi Kato, Yuto Sugawara, Runa Shimizu, Tomotari Inami, Kenji Kawai, Shun Matsubara, Risa Tanaka, Makoto Suzuki, Shintaro Shimozawa, Yuta Hotchi, Ippei Osugi, Risa Katou, Sakurako Ito, Kentaro Mishima, Akihiko Kondo, Keiko Mizuno, Hiroki Takami, Takayuki Komatsu, Tomohisa Nomura and Manabu Sugita | ||||
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| Corresponding Author | Daisuke Usuda, Associate Professor, MD, PhD, Department of Emergency and Critical Care Medicine, Juntendo University Nerima Hospital, 3-1-10, Takanodai, Nerima 177-8521, Tokyo, Japan. d.usuda.qa@juntendo.ac.jp | ||||
| Key Words | Acyclovir-resistant herpes encephalitis; Recurrence; Immunocompromised status; Neurosurgical interventions; Treatment; Case report | ||||
| Core Tip | Acyclovir-resistant herpes simplex virus strains have emerged and gradually increased. We report the first case of acyclovir-resistant herpes encephalitis (ARHE) recurring in an immunocompromised adult patient without neurosurgical interventions. Clinicians should recognize this condition because treatment for ARHE is limited, and it often develops into severe herpes disease that is refractory to antiviral drug therapy. In addition, ARHE recurred in the patient following remission; therefore, it is necessary to discuss the length of the treatment period. There is no established standard treatment for recurrence cases; therefore, accumulation of evidence is needed. | ||||
| Publish Date | 2025-12-05 06:43 | ||||
| Citation | Usuda D, Furukawa D, Imaizumi R, Ono R, Kaneoka Y, Nakajima E, Kato M, Sugawara Y, Shimizu R, Inami T, Kawai K, Matsubara S, Tanaka R, Suzuki M, Shimozawa S, Hotchi Y, Osugi I, Katou R, Ito S, Mishima K, Kondo A, Mizuno K, Takami H, Komatsu T, Nomura T, Sugita M. Recurrence of acyclovir-resistant herpes encephalitis in an immunocompromised patient: A case report. World J Clin Cases 2025; 13(34): 111438 |
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| URL | https://www.wjgnet.com/2307-8960/full/v13/i34/111438.htm | ||||
| DOI | https://dx.doi.org/10.12998/wjcc.v13.i34.111438 |
| Full Article (PDF) | WJCC-13-111438-with-cover.pdf |
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| CARE Checklist–2016 | 111438-CARE-Checklist-2016.pdf |
| Manuscript File | 111438_Auto_Edited_021327.docx |
| Answering Reviewers | 111438-answering-reviewers.pdf |
| Audio Core Tip | 111438-audio.m4a |
| Conflict-of-Interest Disclosure Form | 111438-conflict-of-interest-statement.pdf |
| Copyright License Agreement | 111438-copyright-assignment.pdf |
| Signed Consent for Treatment Form(s) or Document(s) | 111438-informed-consent-statement.pdf |
| Non-Native Speakers of English Editing Certificate | 111438-non-native-speakers.pdf |
| Peer-review Report | 111438-peer-reviews.pdf |
| Scientific Misconduct Check | 111438-scientific-misconduct-check.png |
| Scientific Editor Work List | 111438-scientific-editor-work-list.pdf |
| CrossCheck Report | 111438-crosscheck-report.pdf |