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Articles Published Processes
10/24/2025 7:36:28 AM | Browse: 139 | Download: 92
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Received |
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2025-07-01 06:38 |
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Peer-Review Started |
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2025-07-01 06:38 |
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First Decision by Editorial Office Director |
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2025-07-18 07:22 |
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Return for Revision |
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2025-07-18 07:22 |
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Revised |
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2025-08-01 00:37 |
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Publication Fee Transferred |
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2025-08-03 09:14 |
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Second Decision by Editor |
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2025-08-25 03:48 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-25 09:28 |
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Articles in Press |
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2025-08-25 09:28 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-13 00:22 |
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Publish the Manuscript Online |
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2025-10-24 07:36 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Reduction in the hepatocellular carcinoma antioncogene SLC39A14 during the malignant progression of hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wei Guo, Ming-Xuan Wang, Tong Mu, Kan Xu, Zhao-Di Jiang, Xue-Hua Wan, Jun-Wei Li and Yong-Xiang Yi |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Postgraduate Research & Practice Innovation Program of Jiangsu Province |
SJCX23-0857 |
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| Corresponding Author |
Yong-Xiang Yi, MD, PhD, Clinical Research Center, The Second Hospital of Nanjing, Affiliated to Nanjing University of Chinese Medicine, No. 1 Kangfu Road, Tangshan Subdistrict, Jiangning District, Nanjing 211113, Jiangsu Province, China. ian0126@126.com |
| Key Words |
Apoptosis; Epithelial–mesenchymal transition; Hepatocellular carcinoma |
| Core Tip |
This study's findings associate SLC39A14 downregulation with hepatocellular carcinoma (HCC) progression. SLC39A14 overexpression inhibits HCC cell proliferation, migration, and invasion while promoting apoptosis via the BCL-2/BAX/caspase-3 pathway. Bioinformatics analysis suggests that STAT3 regulates the expression of SLC39A14. Our findings together highlight SLC39A14-BCL-2/BAX/caspase-3 and SLC39A14-EMT axes as potential therapeutic targets for HCC. |
| Publish Date |
2025-10-24 07:36 |
| Citation |
Guo W, Wang MX, Mu T, Xu K, Jiang ZD, Wan XH, Li JW, Yi YX. Reduction in the hepatocellular carcinoma antioncogene SLC39A14 during the malignant progression of hepatocellular carcinoma. World J Gastrointest Surg 2025; 17(10): 111454 |
| URL |
https://www.wjgnet.com/1948-9366/full/v17/i10/111454.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v17.i10.111454 |
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