| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Twenty-year temporal trends, risk profiles, and prognostic value of clinicopathological features in gallbladder cancer following cholecystectomy
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jeongyeon An, So-Hyun Ahn, Kyung-Hee Kim, Jun Young Heo and Min-Kyung Yeo |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Korea Health Technology R&D Project Through the Korea Health Industry Development Institute funded by the Ministry of Health & Welfare, Republic of Korea |
RS-2020-KH088690 |
| National Research Foundation of Korea Grants funded by the Korean Government (MSIT) |
RS-2024-00406568 |
|
| Corresponding Author |
Min-Kyung Yeo, Associate Professor, PhD, Department of Pathology, Chungnam National University School of Medicine, Munwha-ro 266, Daejeon 35015, South Korea. mkyeo83@gmail.com |
| Key Words |
Gallbladder cancer; Cholecystectomy; Risk factors; Time factors; Prognosis |
| Core Tip |
This study examined temporal trends, clinicopathological features, and survival outcomes in post-cholecystectomy gallbladder cancer to identify risk factors for early detection and management. In this single-institutional study, our findings may be limited but still provide insights. Age, hypertension, cholangitis, and serological markers including total cholesterol, triglyceride, albumin were risk factors for cancer and related to survival outcomes. Pathological features, such as tumor budding, tumor size, and poorly cohesive or undifferentiated components were correlated with worse prognosis. These findings emphasize the value of early identification of high-risk profiles and the prognostic markers of gallbladder cancer. |
| Publish Date |
2026-02-06 08:53 |
| Citation |
An J, Ahn SH, Kim KH, Heo JY, Yeo MK. Twenty-year temporal trends, risk profiles, and prognostic value of clinicopathological features in gallbladder cancer following cholecystectomy. World J Gastroenterol 2026; 32(7): 111478 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i7/111478.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i7.111478 |
