BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
8/21/2025 5:29:16 AM | Browse: 64 | Download: 137
 |
Received |
|
2025-07-01 09:16 |
|
Peer-Review Started |
|
2025-07-01 09:16 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2025-07-17 10:13 |
|
Revised |
|
2025-07-31 08:32 |
|
Second Decision |
|
2025-08-07 02:41 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2025-08-07 07:31 |
|
Articles in Press |
|
2025-08-07 07:31 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-08-13 02:27 |
|
Publish the Manuscript Online |
|
2025-08-21 05:29 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Editorial |
| Article Title |
L-arginine: A promising metabolite in enhancing the protective effects of adipose-derived stem cells against ischemic pathologies
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Na Liu, Xin-Xing Wan, Wei-Tao Yan and Kun Xiong |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82303047, 82372507, 82172196, 32401046 |
| Natural Science Foundation of Hunan Province |
2022JJ40801 |
|
| Corresponding Author |
Kun Xiong, Department of Anatomy and Neurobiology, School of Basic Medical Science, Central South University, No. 172 Tongzipo Road, Changsha 410013, Hunan Province, China. xiongkun2001@163.com |
| Key Words |
L-arginine; Metabolite; Bone marrow-derived mesenchymal stem cells; Adipose tissue-derived mesenchymal stem cells; Ischemic pathologies |
| Core Tip |
Ischemic pathologies impose global health challenges and economic burden due to limited therapeutic efficacy. Li et al revealed that the metabolite L-arginine, enriched in adipose tissue-derived mesenchymal stem cells (ADSCs) obtained from elderly patients, could enhance the therapeutic efficacy of ADSCs by promoting angiogenesis and inhibiting cell apoptosis in ischemic conditions. This research underscores the significance of L-arginine for ADSCs-based therapy from a metabolic perspective, highlighting the potential of combining metabolic modulation with ADSCs therapy to improve clinical outcomes in ischemic diseases, particularly in aging populations. However, additional clinical studies are essential to validate the clinical application of these findings. |
| Publish Date |
2025-08-21 05:29 |
| Citation |
<p>Liu N, Wan XX, Yan WT, Xiong K. L-arginine: A promising metabolite in enhancing the protective effects of adipose-derived stem cells against ischemic pathologies. <i>World J Stem Cells</i> 2025; 17(8): 111497</p> |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i8/111497.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i8.111497 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
