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3/6/2026 8:56:31 AM | Browse: 3 | Download: 14
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 111501
Country Egypt
Received
2025-07-01 09:23
Peer-Review Started
2025-07-01 09:24
First Decision by Editorial Office Director
2025-08-06 10:36
Return for Revision
2025-08-06 10:36
Revised
2025-08-07 21:13
Publication Fee Transferred
Second Decision by Editor
2025-11-14 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-14 06:38
Articles in Press
2025-11-14 06:38
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-03 00:37
Publish the Manuscript Online
2026-03-06 08:56
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Systematic Reviews
Article Title Gastrointestinal consequences of cesarean section birth: A systematic review of short- and long-term effects in infancy and beyond
Manuscript Source Invited Manuscript
All Author List Mohammed Al-Beltagi, Salman Alzayani, Nermin Kamal Saeed, Adel Salah Bediwy, Archana Prabu Kumar, Hosameldin A Bediwy and Reem Elbeltagi
ORCID
Author(s) ORCID Number
Mohammed Al-Beltagi http://orcid.org/0000-0002-7761-9536
Salman Alzayani http://orcid.org/0000-0003-2487-5007
Nermin Kamal Saeed http://orcid.org/0000-0001-7875-8207
Adel Salah Bediwy http://orcid.org/0000-0002-0281-0010
Archana Prabu Kumar http://orcid.org/0000-0003-1536-8433
Hosameldin A Bediwy http://orcid.org/0000-0003-2910-8261
Reem Elbeltagi http://orcid.org/0000-0001-9969-5970
Funding Agency and Grant Number
Corresponding Author Mohammed Al-Beltagi, Academic Editor, Chairman, Consultant, Head, MD, PhD, Professor, Department of Pediatrics, Faculty of Medicine, Tanta University, 1 Hassan Radwan Street, Tanta 31511, Algharbia, Egypt. mbelrem@hotmail.com
Key Words Cesarean section; Gut microbiota; Infantile colic; Functional gastrointestinal disorders; Food allergy; Inflammatory bowel disease; Dysbiosis; Probiotics; Breastfeeding
Core Tip Cesarean section (C-section) delivery is associated with altered neonatal gut microbiota and a higher risk of both short- and long-term gastrointestinal (GI) disorders. This systematic review summarizes evidence linking C-section to infantile colic, gastroesophageal reflux, constipation, food allergies, inflammatory bowel disease, and celiac disease. The review highlights gut dysbiosis as a central mechanism and identifies modifiable factors—including breastfeeding, probiotic use, and reduced antibiotic exposure—that can mitigate risks. Understanding these associations enables clinicians to provide personalized postnatal care and early interventions that may prevent chronic GI outcomes in C-section-born infants.
Publish Date 2026-03-06 08:56
Citation

Al-Beltagi M, Alzayani S, Saeed NK, Bediwy AS, Prabu Kumar A, Bediwy HA, Elbeltagi R. Gastrointestinal consequences of cesarean section birth: A systematic review of short- and long-term effects in infancy and beyond. World J Clin Pediatr 2026; 15(1): 111501

URL https://www.wjgnet.com/2219-2808/full/v15/i1/111501.htm
DOI https://dx.doi.org/10.5409/wjcp.v15.i1.111501
Full Article (PDF) WJCP-15-111501-with-cover.pdf
PRISMA 2009 Checklist 111501-PRISMA-2009-Checklist.pdf
Manuscript File 111501_Auto_Edited_030403.docx
Answering Reviewers 111501-answering-reviewers.pdf
Audio Core Tip 111501-audio.mp3
Biostatistics Review Certificate 111501-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111501-conflict-of-interest-statement.pdf
Copyright License Agreement 111501-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 111501-non-native-speakers.pdf
Peer-review Report 111501-peer-reviews.pdf
Scientific Misconduct Check 111501-scientific-misconduct-check.png
Scientific Editor Work List 111501-scientific-editor-work-list.pdf
CrossCheck Report 111501-crosscheck-report.pdf