Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	111509
Country	China

Received	2025-07-08 09:51
Peer-Review Started	2025-07-08 09:51
To Make the First Decision
Return for Revision	2025-07-30 06:39
Revised	2025-08-20 15:20
Second Decision	2025-09-24 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-24 07:14
Articles in Press	2025-09-24 07:14
Publication Fee Transferred	2025-08-26 07:43
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-09-28 01:06
Publish the Manuscript Online	2025-10-14 07:42

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Gut microbiota and metabolite changes in metastatic colorectal cancer via 16S rRNA and metabolomics
Manuscript Source	Unsolicited Manuscript
All Author List	Pan Deng, Hua Lin, Hu Zeng and Feng Guo
ORCID	Author(s) ORCID Number Pan Deng http://orcid.org/0009-0004-0901-5679 Hua Lin http://orcid.org/0009-0000-3406-1707 Hu Zeng http://orcid.org/0009-0001-2045-1541 Feng Guo http://orcid.org/0009-0004-7608-0884
Funding Agency and Grant Number
Corresponding Author	Feng Guo, MD, Department of Interventional Diagnosis and Treatment, The Central Hospital of Yongzhou, No. 396 Yiyun Road, Lengshuitan District, Yongzhou 425002, Hunan Province, China. search_gf@163.com
Key Words	Gut microbiota; Colorectal cancer; Untargeted metabolomics; 16S rRNA sequencing; Liquid chromatography-mass spectrometry
Core Tip	Colorectal cancer patients with different metastatic statuses exhibit distinct gut microbiota and metabolite profiles. These differences may contribute to cancer progression and metastasis, providing potential biomarkers for early diagnosis and therapeutic targets.
Publish Date	2025-10-14 07:42
Citation	<p>Deng P, Lin H, Zeng H, Guo F. Gut microbiota and metabolite changes in metastatic colorectal cancer via 16S rRNA and metabolomics. <i>World J Gastrointest Oncol</i> 2025; 17(10): 111509</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i10/111509.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i10.111509

Full Article (PDF)	WJGO-17-111509-with-cover.pdf
STROBE Statement	111509-STROBE-statement.pdf
Manuscript File	111509_Auto_Edited_080432.docx
Answering Reviewers	111509-answering-reviewers.pdf
Audio Core Tip	111509-audio.m4a
Biostatistics Review Certificate	111509-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	111509-conflict-of-interest-statement.pdf
Copyright License Agreement	111509-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	111509-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	111509-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	111509-non-native-speakers.pdf
Peer-review Report	111509-peer-reviews.pdf
Scientific Misconduct Check	111509-scientific-misconduct-check.png
Scientific Editor Work List	111509-scientific-editor-work-list.pdf
CrossCheck Report	111509-crosscheck-report.pdf