Publication Name	World Journal of Clinical Cases
Manuscript ID	111525
Country	China

Received	2025-07-02 06:18
Peer-Review Started	2025-07-02 06:18
To Make the First Decision
Return for Revision	2025-07-16 08:28
Revised	2025-07-25 07:26
Second Decision	2025-10-14 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-10-14 08:31
Articles in Press	2025-10-14 08:31
Publication Fee Transferred	2025-07-27 05:07
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-11-07 07:09
Publish the Manuscript Online	2025-11-12 09:50

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Medicine, General & Internal
Manuscript Type	Case Report
Article Title	Atypical sarcoidosis diagnosed using endobronchial ultrasound-guided mediastinal lymph node biopsy with fine biopsy forceps: Two case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Wen-Xuan Yu, Feng-Fu Zhan, Ping-Yang Hong, Mao-Hong Huang, Yi-Yuan Chen, Yi-Li Lin and Xiao-Bin Zhang
ORCID	Author(s) ORCID Number Xiao-Bin Zhang http://orcid.org/0000-0002-5155-8560
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82170103 Natural Science Foundation of Fujian Province 2024J011325 Young people training project from Fujian Province Health Bureau 2020GGB057 Youth Research Project from Fujian Province Health Bureau 2023QNB008 Xiamen Medical and Health Guidance Project 3502Z20224ZD1060 Xiamen Medical and Health Guidance Project 3502Z20214ZD1043 Xiamen Medical and Health Guidance Project 3502Z20224ZD1058
Corresponding Author	Xiao-Bin Zhang, Department of Pulmonary and Critical Care Medicine, School of Medicine, Zhongshan Hospital Xiamen University, No. 201-209 Hubinnan Road, Siming District, Xiamen 361004, Fujian Province, China. zhangxiaobincn@xmu.edu.cn
Key Words	Sarcoidosis; Endobronchial ultrasound; Transbronchial forceps biopsy; Non-caseating granuloma; Mediastinal lymph node biopsy; Case report
Core Tip	This report highlights the diagnostic value of endobronchial ultrasound-guided transbronchial forceps biopsy (EBUS-TBFB) for atypical sarcoidosis. In two asymptomatic cases with non-specific imaging mimicking malignancy, conventional EBUS-guided fine-needle aspiration yielded inconclusive cytology. By contrast, EBUS-TBFB - using a 1.2-mm forceps via the same puncture site - obtained larger histological samples (≥ 3 mm), confirming non-caseating granulomas. This technique overcomes transbronchial needle aspiration’s limitations for benign diseases, improving diagnostic accuracy and guiding critical management decisions: Observation for localized disease (Case 1) or timely immunosuppression for systemic involvement (Case 2). EBUS-TBFB is a promising tool for radiologically ambiguous sarcoidosis.
Publish Date	2025-11-12 09:50
Citation	<p>Yu WX, Zhan FF, Hong PY, Huang MH, Chen YY, Lin YL, Zhang XB. Atypical sarcoidosis diagnosed using endobronchial ultrasound-guided mediastinal lymph node biopsy with fine biopsy forceps: Two case reports. <i>World J Clin Cases</i> 2025; 13(32): 111525</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i32/111525.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i32.111525

Full Article (PDF)	WJCC-13-111525-with-cover.pdf
CARE Checklist–2016	111525-CARE-Checklist-2016.pdf
Manuscript File	111525_Auto_Edited_080636.docx
Answering Reviewers	111525-answering-reviewers.pdf
Audio Core Tip	111525-audio.mp3
Conflict-of-Interest Disclosure Form	111525-conflict-of-interest-statement.pdf
Copyright License Agreement	111525-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s)	111525-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	111525-non-native-speakers.pdf
Peer-review Report	111525-peer-reviews.pdf
Scientific Misconduct Check	111525-scientific-misconduct-check.png
Scientific Editor Work List	111525-scientific-editor-work-list.pdf
CrossCheck Report	111525-crosscheck-report.pdf