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Articles Published Processes
3/26/2026 9:22:58 AM | Browse: 3 | Download: 12
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Received |
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2025-07-03 12:34 |
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Peer-Review Started |
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2025-07-03 12:34 |
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First Decision by Editorial Office Director |
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2025-07-16 08:41 |
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Return for Revision |
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2025-07-16 08:41 |
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Revised |
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2025-08-20 14:53 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-16 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-16 07:14 |
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Articles in Press |
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2026-01-16 07:14 |
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Edit the Manuscript by Language Editor |
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2026-01-23 00:21 |
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Typeset the Manuscript |
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2026-03-16 11:14 |
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Publish the Manuscript Online |
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2026-03-26 09:22 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Multidisciplinary Sciences |
| Manuscript Type |
Retrospective Study |
| Article Title |
Inflammatory parameters and liver fibrosis in patients with steatosis: A cross-sectional analysis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Melina Borba Duarte, Juliana Czermainski, Luis F Ferreira, Cristiane V Tovo and Randhall B Carteri |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Cristiane V Tovo, Department of Internal Medicine, Federal University of Health Sciences of Porto Alegre, R. Sarmento Leite, 245 - Centro Histórico, Porto Alegre - RS, 90050-170, Porto Alegre 90050-170, Rio Grande do Sul, Brazil. cristianev@ufcspa.edu.br |
| Key Words |
Hepatology; Systemic inflammation; Neutrophil-to-lymphocyte ratio; C-reactive protein; Liver fibrosis; Inflammatory markers; Systemic inflammation |
| Core Tip |
This study evaluated low-cost inflammatory indices derived from whole blood cell counts-such as neutrophile to lymphocyte ratio, aggregate index of systemic inflammation, and systemic inflammation response index, as potential non-invasive tools to predict liver fibrosis in adults with metabolic dysfunction-associated steatotic liver disease using National Health and Nutrition Examination Survey data. Although these indices showed statistically significant associations with liver damage, their overall predictive accuracy was limited, with no positive predictive value and low area under the curve. C-reactive protein consistently outperformed the cell-based indices. These findings suggest that while inflammatory ratios are easy to calculate, they are insufficient as standalone markers for fibrosis prediction, highlighting the need to explore more accurate and cost-effective direct biomarkers. |
| Publish Date |
2026-03-26 09:22 |
| Citation |
Duarte MB, Czermainski J, Ferreira LF, Tovo CV, Carteri RB. Inflammatory parameters and liver fibrosis in patients with steatosis: A cross-sectional analysis. World J Hepatol 2026; 18(3): 111569 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i3/111569.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i3.111569 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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