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11/13/2025 6:51:07 AM | Browse: 11 | Download: 46
Publication Name World Journal of Gastroenterology
Manuscript ID 111708
Country China
Received
2025-07-14 12:05
Peer-Review Started
2025-07-14 12:07
To Make the First Decision
Return for Revision
2025-07-24 09:00
Revised
2025-08-06 12:34
Second Decision
2025-10-11 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-10-11 05:25
Articles in Press
2025-10-11 05:25
Publication Fee Transferred
2025-08-07 07:05
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-05 09:17
Publish the Manuscript Online
2025-11-13 06:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Unveiling Yiyi Fuzi Baijiang powder: Microecological and network pharmacology approach to ulcerative colitis treatment
Manuscript Source Unsolicited Manuscript
All Author List Liang-Kun Zhang, Wen-Chao Gu and Jian Chen
ORCID
Author(s) ORCID Number
Liang-Kun Zhang http://orcid.org/0000-0002-4528-6968
Wen-Chao Gu http://orcid.org/0000-0002-0433-082X
Jian Chen http://orcid.org/0000-0002-1140-2780
Funding Agency and Grant Number
Funding Agency Grant Number
Key Project at Central Government Level No. 2060302
Key Project of Traditional Chinese Medicine Science and Technology in Shandong Province No. Z-2023015
Clinical Medical Science and Technology Innovation Program of Jinan Science and Technology Bureau No. 202328043
Corresponding Author Jian Chen, MD, PhD, Jinan Central Hospital Affiliated to Shandong First Medical University, No. 105 Jiefang Road, Lixia District, Jinan 250355, Shandong Province, China. chenjian860103@163.com
Key Words Yiyi Fuzi Baijiang powder; Chinese medicine; Ulcerative colitis; Gut microbiota; Microbiome; Intestinal flora; Network pharmacology; Molecular docking; Mechanism
Core Tip The therapeutic application of Yiyi Fuzi Baijiang powder (YFB) for ulcerative colitis (UC) extends beyond merely altering the structure and abundance of gut microbiota. Instead, it aims to restore dynamic equilibrium by comprehensively modulating the intestinal microecological balance, thereby facilitating disease recovery. Furthermore, it is hypothesized that YFB powder may exert its effects on UC through potential mechanisms involving the NFKB1, RELA, and nuclear factor kappa B inhibitor alpha regulatory pathways, as well as the cancer and adipocytokine signaling pathways.
Publish Date 2025-11-13 06:51
Citation <p>Zhang LK, Gu WC, Chen J. Unveiling Yiyi Fuzi Baijiang powder: Microecological and network pharmacology approach to ulcerative colitis treatment. <i>World J Gastroenterol</i> 2025; 31(42): 111708</p>
URL https://www.wjgnet.com/1007-9327/full/v31/i42/111708.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i42.111708
Full Article (PDF) WJG-31-111708-with-cover.pdf
The ARRIVE Guidelines 111708-The-ARRIVE-Guidelines.pdf
Manuscript File 111708_Auto_Edited_075802.docx
Answering Reviewers 111708-answering-reviewers.pdf
Audio Core Tip 111708-audio.wav
Biostatistics Review Certificate 111708-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111708-conflict-of-interest-statement.pdf
Copyright License Agreement 111708-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 111708-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate 111708-non-native-speakers.pdf
Supplementary Material 111708-supplementary-material.pdf
Peer-review Report 111708-peer-reviews.pdf
Scientific Misconduct Check 111708-scientific-misconduct-check.png
Scientific Editor Work List 111708-scientific-editor-work-list.pdf
CrossCheck Report 111708-crosscheck-report.pdf