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12/23/2025 8:03:21 AM | Browse: 10 | Download: 14
Publication Name World Journal of Nephrology
Manuscript ID 111723
Country Thailand
Received
2025-07-08 05:44
Peer-Review Started
2025-07-08 05:45
First Decision by Editorial Office Director
2025-08-14 08:30
Return for Revision
2025-08-14 08:30
Revised
2025-08-23 03:22
Publication Fee Transferred
2025-08-25 02:16
Second Decision by Editor
2025-10-20 02:57
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-21 02:32
Articles in Press
2025-10-21 02:32
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-16 00:22
Publish the Manuscript Online
2025-12-23 08:03
ISSN 2220-6124 (online)
Open Access Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Case Report
Article Title Tacrolimus toxicity in kidney transplant recipient after wedge liver resection: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Nuanjanthip Naiyarakseree, Thunyatorn Wuttiputhanun, Natavudh Townamchai, Methee Sutherasan, Yingyos Avihingsanon and Suwasin Udomkarnjananun
ORCID
Author(s) ORCID Number
Suwasin Udomkarnjananun http://orcid.org/0000-0003-4087-9032
Funding Agency and Grant Number
Corresponding Author Suwasin Udomkarnjananun, Assistant Professor, Lecturer, MD, PhD, Researcher, Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873, Rama 4 road, Pathumwan, Bangkok 10330, Krung Thep Maha Nakhon, Thailand. suwasin.u@gmail.com
Key Words Tacrolimus; Kidney transplant; Liver resection; Hepatectomy; Nephrotoxicity; Neurotoxicity; Case report
Core Tip We report the first case of tacrolimus toxicity in a kidney-transplant recipient after wedge liver resection for hepatocellular carcinoma. Reduced liver mass and transient ischemic injury impaired metabolism of tacrolimus, a calcineurin inhibitor, causing rapid rises in trough concentration, acute kidney injury, and neurotoxicity that reversed with dose interruption. The case underscores the need for proactive therapeutic drug monitoring, early dose adjustment, and structured evaluation of postoperative acute kidney injury in transplant recipients undergoing hepatic surgery.
Publish Date 2025-12-23 08:03
Citation

Naiyarakseree N, Wuttiputhanun T, Townamchai N, Sutherasan M, Avihingsanon Y, Udomkarnjananun S. Tacrolimus toxicity in kidney transplant recipient after wedge liver resection: A case report and review of literature. World J Nephrol 2025; 14(4): 111723

URL https://www.wjgnet.com/2220-6124/full/v14/i4/111723.htm
DOI https://dx.doi.org/10.5527/wjn.v14.i4.111723
Full Article (PDF) WJN-14-111723-with-cover.pdf
CARE Checklist–2016 111723-CARE-Checklist-2016.pdf
Manuscript File 111723_Auto_Edited_020254.docx
Answering Reviewers 111723-answering-reviewers.pdf
Audio Core Tip 111723-audio.mp3
Conflict-of-Interest Disclosure Form 111723-conflict-of-interest-statement.pdf
Copyright License Agreement 111723-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 111723-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 111723-non-native-speakers.pdf
Peer-review Report 111723-peer-reviews.pdf
Scientific Misconduct Check 111723-scientific-misconduct-check.png
Scientific Editor Work List 111723-scientific-editor-work-list.pdf
CrossCheck Report 111723-crosscheck-report.pdf