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1/15/2026 8:12:51 AM | Browse: 1 | Download: 1
Publication Name World Journal of Cardiology
Manuscript ID 111736
Country Croatia
Received
2025-07-08 08:14
Peer-Review Started
2025-07-08 08:14
First Decision by Editorial Office Director
2025-07-17 10:16
Return for Revision
2025-07-17 10:16
Revised
2025-07-28 18:45
Publication Fee Transferred
Second Decision by Editor
2025-12-03 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-03 06:23
Articles in Press
2025-12-03 06:23
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-08 00:33
Publish the Manuscript Online
2026-01-15 08:12
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Prospective Study
Article Title Impact of total occlusion of the infarct-related coronary artery on mortality of 2483 patients with acute myocardial infarction
Manuscript Source Invited Manuscript
All Author List Nikola Kos, Ivan Zeljković, Karlo Golubic, Vjekoslav Radeljic, Marijan Erceg, Diana Delic-Brkljacic, Maja Cigrovski Berkovic and Nikola Bulj
ORCID
Author(s) ORCID Number
Nikola Kos http://orcid.org/0000-0001-8829-2543
Ivan Zeljković http://orcid.org/0000-0002-4550-4056
Karlo Golubic http://orcid.org/0000-0003-0684-6333
Vjekoslav Radeljic http://orcid.org/0000-0003-2471-4035
Marijan Erceg http://orcid.org/0000-0002-7720-9422
Diana Delic-Brkljacic http://orcid.org/0000-0002-7116-2360
Maja Cigrovski Berkovic http://orcid.org/0000-0003-0750-9785
Nikola Bulj http://orcid.org/0000-0002-7859-3374
Funding Agency and Grant Number
Corresponding Author Nikola Kos, MD, PhD, Department of Cardiology, University Hospital Centre Sestre Milosrdnice, Vinogradska 29, Zagreb 10000, Croatia. nikolakos89@gmail.com
Key Words Infarct-related artery; Coronary artery occlusion; Myocardial infarction; Short-term mortality; Statin therapy; Coronary angiography
Core Tip This large prospective study found that culprit coronary artery occlusion worsens the prognosis at 30 days, regardless of the electrocardiographic presentation. Patients with occluded arteries are younger and exhibited more severe clinical features, while those with patent arteries were older and had more chronic issues. The presence of occlusion increased the risk of short-term mortality threefold. Chronic statin use prior to the acute myocardial infarction was associated with a lower likelihood of artery occlusion. These findings suggest that angiographic assessment of culprit artery patency should be integrated into stratification of acute myocardial infarction beyond traditional ST-elevation /non-ST-segment patterns.
Publish Date 2026-01-15 08:12
Citation

Kos N, Zeljković I, Golubic K, Radeljic V, Erceg M, Delic-Brkljacic D, Cigrovski Berkovic M, Bulj N. Impact of total occlusion of the infarct-related coronary artery on mortality of 2483 patients with acute myocardial infarction. World J Cardiol 2026; 18(1): 111736

URL https://www.wjgnet.com/1949-8462/full/v18/i1/111736.htm
DOI https://dx.doi.org/10.4330/wjc.v18.i1.111736
Full Article (PDF) WJC-18-111736-with-cover.pdf
CONSORT 2010 Statement 111736-CONSORT-2010-statement.PDF
Manuscript File 111736_Auto_Edited_090218.docx
Answering Reviewers 111736-answering-reviewers.pdf
Audio Core Tip 111736-audio.wav
Biostatistics Review Certificate 111736-biostatistics-statement.pdf
Clinical Trial Registration Statement 111736-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 111736-conflict-of-interest-statement.pdf
Copyright License Agreement 111736-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111736-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111736-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111736-non-native-speakers.pdf
Peer-review Report 111736-peer-reviews.pdf
Scientific Misconduct Check 111736-scientific-misconduct-check.png
Scientific Editor Work List 111736-scientific-editor-work-list.pdf
CrossCheck Report 111736-crosscheck-report.pdf