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Articles Published Processes
11/27/2025 9:20:15 AM | Browse: 9 | Download: 30
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Received |
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2025-07-29 08:54 |
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Peer-Review Started |
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2025-07-29 08:54 |
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First Decision by Editorial Office Director |
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2025-08-19 06:41 |
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Return for Revision |
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2025-08-19 06:41 |
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Revised |
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2025-08-31 13:39 |
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Publication Fee Transferred |
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2025-09-06 01:21 |
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Second Decision by Editor |
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2025-10-14 02:49 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-14 06:54 |
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Articles in Press |
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2025-10-14 06:54 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-18 06:40 |
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Publish the Manuscript Online |
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2025-11-27 09:20 |
| ISSN |
2220-3206 (online) |
| Open Access |
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychology, Clinical |
| Manuscript Type |
Basic Study |
| Article Title |
Correlation between anxiety-depression disorders and brain structural connectivity abnormalities after subarachnoid hemorrhage
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lei Qin, Kai Wang, Li-Ping Jiang, Zhang Xiao and Song Luo |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Clinical Medicine Research and Translational Project of Anhui Province |
202204295107020036, 202304295107020076 |
| the Science and Technology Innovation Guidance Project of Bengbu City |
20200338 |
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| Corresponding Author |
Lei Qin, Department of Radiology, The First Affiliated Hospital of Bengbu Medical University, No. 801, Zhihuai Road, Bengbu 233004, Anhui Province, China. 15155296160@163.com |
| Key Words |
Subarachnoid hemorrhage; Anxiety; Depression; Diffusion tensor imaging; Neuroinflammation; Limbic-prefrontal circuit |
| Core Tip |
Post-subarachnoid hemorrhage anxiety-depression disorders follow a temporal cascade of early neuroinflammation (interleukin-1β elevation) leading to progressive limbic-prefrontal circuit damage. Strong correlations between cerebrospinal fluid inflammatory markers and behavioral deficits suggest central inflammation drives emotional dysfunction. This study emphasizes the correlation between anxiety and depression after subarachnoid hemorrhage and abnormal brain structural connections: Damage to the white matter microstructure centered on the limbic prefrontal lobe, corpus callosum, and thalamic-cortical fibers reduces network efficiency and is significantly associated with the severity of symptoms. Diffusion tensor imaging/structural connectome indicators (fractional anisotropy, mean diffusivity, global efficiency) can serve as imaging biomarkers for risk stratification and prognosis assessment, supporting early identification and targeted neuropsychological intervention. |
| Publish Date |
2025-11-27 09:20 |
| Citation |
Qin L, Wang K, Jiang LP, Xiao Z, Luo S. Correlation between anxiety-depression disorders and brain structural connectivity abnormalities after subarachnoid hemorrhage. World J Psychiatry 2025; 15(12): 111754 |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i12/111754.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i12.111754 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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