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Articles Published Processes
12/31/2025 5:47:39 AM | Browse: 3 | Download: 24
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Received |
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2025-07-10 06:32 |
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Peer-Review Started |
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2025-07-10 06:32 |
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First Decision by Editorial Office Director |
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2025-07-17 08:37 |
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Return for Revision |
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2025-07-17 08:37 |
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Revised |
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2025-08-12 14:59 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-22 02:12 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-29 06:39 |
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Articles in Press |
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2025-10-29 06:39 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-18 12:17 |
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Publish the Manuscript Online |
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2025-12-31 05:47 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychology, Clinical |
| Manuscript Type |
Minireviews |
| Article Title |
Differential diagnosis of bipolar II disorder and major depressive disorder: Integrating multimodal approaches to overcome clinical challenges
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yuan-Zi Zou, Ting Chen and Chao-Ban Wang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Chao-Ban Wang, Department of Pediatrics Hematology, West China Second University Hospital, Sichuan University, No. 1416 Chenglong Avenue, Jinjiang District, Chengdu 610000, Sichuan Province, China. chaobanwang@scu.edu.cn |
| Key Words |
Bipolar II disorder; Major depressive disorder; Clinical symptoms; Biomarkers; Neuroimaging |
| Core Tip |
A multidisciplinary approach that combines detailed clinical evaluation, insights into genetic underpinnings, and multimodal assessments using neuroimaging and biomarkers may substantially improve clinicians’ ability to distinguish between major depressive disorder (MDD) and bipolar II disorder (BD-II). Enhanced diagnostic accuracy can lead to more tailored and effective treatment strategies, ultimately improving patients' health outcomes and quality of life. This mini-review aims to summarize current evidence on the distinguishing features of MDD and BD-II-focusing on clinical symptoms, genetic profiles, neuroimaging findings, and biomarker signatures-and discusses the potential of machine learning approaches to further refine and support the differential diagnostic process. |
| Publish Date |
2025-12-31 05:47 |
| Citation |
Zou YZ, Chen T, Wang CB. Differential diagnosis of bipolar II disorder and major depressive disorder: Integrating multimodal approaches to overcome clinical challenges. World J Psychiatry 2026; 16(1): 111800 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i1/111800.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i1.111800 |
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