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Articles Published Processes
11/27/2025 9:20:14 AM | Browse: 20 | Download: 47
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Received |
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2025-07-11 05:38 |
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Peer-Review Started |
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2025-07-11 05:38 |
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First Decision by Editorial Office Director |
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2025-08-04 06:56 |
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Return for Revision |
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2025-08-04 06:56 |
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Revised |
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2025-08-15 03:53 |
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Publication Fee Transferred |
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2025-08-20 08:46 |
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Second Decision by Editor |
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2025-10-11 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-11 07:12 |
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Articles in Press |
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2025-10-11 07:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-18 06:39 |
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Publish the Manuscript Online |
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2025-11-27 09:20 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychology, Clinical |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Efficacy and mechanism of Shugan Jieyu combined with sertraline in alcohol-dependent patients with depression: A randomized clinical study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan Zhang, Hao-Yu Xing and Juan Yan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Juan Yan, Manager, MD, Professor, Graduate School, Zhejiang Chinese Medical University, No. 305 Tianmushan Road, Xihu District, Hangzhou 311402, Zhejiang Province, China. 294162939@qq.com |
| Key Words |
Mechanism; Efficacy; Depression; Alcohol dependence; Sertraline; Shugan Jieyu capsules |
| Core Tip |
This study investigates the efficacy and safety of combining Shugan Jieyu capsules (SJC) with sertraline in treating alcohol dependence and comorbid depression. The results show that the combination significantly reduces depression symptoms, with improved outcomes seen as early as 2 weeks. The study group demonstrated a higher total efficacy rate (90%) compared to the control group (73.3%), with no significant difference in adverse reactions between the two groups. These findings suggest that SJC, when used alongside sertraline, offer a promising, safe, and effective treatment option for patients with alcohol-induced depression. |
| Publish Date |
2025-11-27 09:20 |
| Citation |
Zhang Y, Xing HY, Yan J. Efficacy and mechanism of Shugan Jieyu combined with sertraline in alcohol-dependent patients with depression: A randomized clinical study. World J Psychiatry 2025; 15(12): 111801 |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i12/111801.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i12.111801 |
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