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Articles Published Processes
12/31/2025 5:47:38 AM | Browse: 3 | Download: 17
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Received |
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2025-07-11 05:43 |
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Peer-Review Started |
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2025-07-11 05:44 |
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First Decision by Editorial Office Director |
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2025-07-22 05:53 |
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Return for Revision |
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2025-07-22 05:53 |
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Revised |
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2025-07-30 03:25 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-08 09:59 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-15 08:16 |
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Articles in Press |
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2025-10-15 08:16 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-19 02:33 |
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Publish the Manuscript Online |
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2025-12-31 05:47 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Protective effect of Guanxinning on antipsychotic-induced cardiac impairment in long-term hospitalized psychiatric patients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Fu-Gang Luo, Hao-Yu Xing, Jun-Jie Wang, Wen-Ye Wu, Kai-Jie Fang, Hai-Dong Song and Juan Yan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Special Project for Supporting the Development of Biomedicine and Health Industry in Hangzhou City |
No. 2022WJC123 |
| Zhejiang Province Traditional Chinese Medicine Science and Technology Plan Project |
No. 2022ZA143 |
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| Corresponding Author |
Juan Yan, Quality Control Office, Affiliated Mental Health Center and Hangzhou Seventh People’s Hospital, Zhejiang University School of Medicine, No. 305 Tianmushan Road, Xihu District, Hangzhou 310013, Zhejiang Province, China. 294162939@qq.com |
| Key Words |
Guanxinning; Antipsychotic drugs; Cardiac function; Schizophrenia; Cardiac protection |
| Core Tip |
This study highlights the cardioprotective effects of Guanxinning in patients with psychiatric disorders undergoing long-term antipsychotic therapy. The intervention significantly improved cardiac function, including shortened QT intervals, reduced myocardial enzyme fluctuations, and increased left ventricular ejection fraction. Notably, Guanxinning also enhanced antioxidant capacity and reduced oxidative stress and inflammation, suggesting its potential to mitigate antipsychotic-induced cardiac damage through anti-apoptotic mechanisms. These findings support its clinical use in protecting the heart of psychiatric patients on prolonged antipsychotic treatment. |
| Publish Date |
2025-12-31 05:47 |
| Citation |
Luo FG, Xing HY, Wang JJ, Wu WY, Fang KJ, Song HD, Yan J. Protective effect of Guanxinning on antipsychotic-induced cardiac impairment in long-term hospitalized psychiatric patients. World J Psychiatry 2026; 16(1): 111840 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i1/111840.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i1.111840 |
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