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Articles Published Processes
1/15/2026 8:12:50 AM | Browse: 3 | Download: 1
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Received |
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2025-07-14 05:35 |
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Peer-Review Started |
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2025-07-14 05:36 |
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First Decision by Editorial Office Director |
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2025-07-30 08:01 |
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2025-07-30 08:01 |
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Revised |
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2025-08-12 11:49 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-20 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-20 07:18 |
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Articles in Press |
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2025-11-20 07:18 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-08 01:25 |
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Publish the Manuscript Online |
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2026-01-15 08:12 |
| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Minireviews |
| Article Title |
Subclinical atrial fibrillation: Implications of recent trials for guideline updates?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Akshyaya Pradhan, Shobhit Shah, Pravesh Vishwakarma and Alok Kumar Singh |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Akshyaya Pradhan, Department of Cardiology, King George's Medical University, Shahmina Road, Lucknow 226003, Uttar Pradesh, India. akshyaya33@gmail.com |
| Key Words |
Atrial high-rate episode; NOAH-AFNET 6; ARTESIA; Apixaban; Bleeding; CHA₂DS₂-VASc score |
| Core Tip |
With the growing use of cardiac implantable electronic devices and smartwatches, detection of subclinical atrial fibrillation (SCAF) is common in up to 30% to 60%, depending on the device and the definition used. The risk of stroke in people with SCAF depends on: the baseline CHA₂DS₂-VASc score and how long the episodes last. Short episodes-those lasting less than six minutes-are generally of uncertain significance. However, when the episodes last longer than 24 hours, the risk of stroke or systemic embolism increases more than threefold. The utility of oral anticoagulation, for preventing stroke in those with SCAF is still under debate. Recently, two studies have looked into this: the NOAH-AFNET 6 was stopped early because fewer events occurred than expected, and enrollment was slow. In contrast, in the ARTESIA trial, apixaban lowered the risk of stroke and systemic embolism by 37%, though it also led to more bleeding. According to current ACC/AHA guidelines, oral anticoagulation is recommended for people who have SCAF episodes lasting more than 24 hours and have a high CHA₂DS₂-VASc score. For those with episodes between six minutes and 24 hours, a more cautious approach is advised-this includes managing risk factors along with regular follow-up. However, the positive results from the ARTESIA study suggest these recommendations may need to be reconsidered. |
| Publish Date |
2026-01-15 08:12 |
| Citation |
Pradhan A, Shah S, Vishwakarma P, Singh AK. Subclinical atrial fibrillation: Implications of recent trials for guideline updates? World J Cardiol 2026; 18(1): 111882 |
| URL |
https://www.wjgnet.com/1949-8462/full/v18/i1/111882.htm |
| DOI |
https://dx.doi.org/10.4330/wjc.v18.i1.111882 |
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