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Articles Published Processes
12/5/2025 11:28:05 AM | Browse: 33 | Download: 119
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Received |
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2025-07-14 03:19 |
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Peer-Review Started |
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2025-07-14 03:19 |
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First Decision by Editorial Office Director |
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2025-08-04 07:51 |
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Return for Revision |
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2025-08-04 07:51 |
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Revised |
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2025-08-15 17:11 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-10 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-10 09:41 |
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Articles in Press |
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2025-11-10 09:41 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-19 07:32 |
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Publish the Manuscript Online |
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2025-12-05 11:28 |
| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Somatostatin-based therapies for external gastrointestinal fistulas: Updated meta-analysis of randomized clinical trials
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Marcelo Augusto Fontenelle Ribeiro Junior, Lucas Fontenelle Vieira, Husna Irfan Thalib, Syed Fouzaan Albeez, Faaleha Heba Fakruddin, Ahmed Mirza Zafar Baig, Hajira Mohammed, Syeda Nafeesa Hashim, Atika Abdul Rauf Khan and Rafael Dib Possiedi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Marcelo Augusto Fontenelle Ribeiro Junior, Chief Physician, Director, FACS, MD, PhD, Professor, Senior Researcher, Department of Surgery, R Adams Cowley Shock Trauma Center, University of Maryland, 22 South Greene Street, Baltimore, Maryland 21201, United States. mrfibeiro@som.umaryland.edu |
| Key Words |
Enterocutaneous fistula; Somatostatin; Octreotide; Meta-analysis; Randomized controlled trials; Time to closure; Length of hospital stay; Conservative treatment; Gastrointestinal surgery |
| Core Tip |
This meta-analysis of nine randomized controlled trials found that somatostatin and its analogues do not increase spontaneous closure rates of external gastrointestinal fistulas compared to standard care. However, treatment significantly shortens hospital stay and time to closure. These benefits suggest that somatostatin-based therapy may be useful as an adjunct in selected patients requiring faster recovery and reduced hospitalization. |
| Publish Date |
2025-12-05 11:28 |
| Citation |
Ribeiro Junior MAF, Fontenelle Vieira L, Thalib HI, Fouzaan Albeez S, Heba Fakruddin F, Mirza Zafar Baig A, Mohammed H, Nafeesa Hashim S, Rauf Khan AA, Dib Possiedi R. Somatostatin-based therapies for external gastrointestinal fistulas: Updated meta-analysis of randomized clinical trials. World J Gastrointest Pharmacol Ther 2025; 16(4): 111889 |
| URL |
https://www.wjgnet.com/2150-5349/full/v16/i4/111889.htm |
| DOI |
https://dx.doi.org/10.4292/wjgpt.v16.i4.111889 |
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