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Articles Published Processes
12/22/2025 7:43:02 AM | Browse: 0 | Download: 0
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Received |
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2025-07-17 03:13 |
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Peer-Review Started |
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2025-07-17 03:13 |
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First Decision by Editorial Office Director |
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2025-08-14 08:20 |
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Return for Revision |
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2025-08-14 08:20 |
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Revised |
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2025-08-18 06:30 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-14 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-14 13:00 |
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Articles in Press |
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2025-11-14 13:00 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-08 06:58 |
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Publish the Manuscript Online |
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2025-12-22 07:43 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Gluten’s silent strike: Unmasking its impact on liver health
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shivam Kalra, Simran Joshi, Manjeet K Goyal, Kartikay Goyal, Bhupender Singh, Ashita R Vuthaluru and Omesh Goyal |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Omesh Goyal, Department of Gastroenterology, Dayanand Medical College and Hospital, Tagore Nagar, Ludhiana 141001, Punjab, India. dromeshgoyal@gmail.com |
| Key Words |
Gluten; Liver dysfunction; Gut-liver axis; Gluten-free diet; Metabolic liver disease; Autoimmune hepatitis; Transaminase elevation; Hepatic steatosis; Celiac hepatitis; Non-celiac gluten sensitivity |
| Core Tip |
Gluten, once viewed solely as a gastrointestinal concern, is now implicated in a wide spectrum of hepatic disorders ranging from mild hypertransaminasemia to cirrhosis. Up to 40% of patients with celiac disease and 9% of those with unexplained elevated liver enzymes may have underlying gluten sensitivity. A gluten-free diet normalizes transaminase levels in most cases, yet long-term adherence may paradoxically exacerbate metabolic liver disease. This article elucidates the complex interplay between gluten, gut permeability, immune activation, and liver pathology. Recognizing gluten’s hepatic implications is crucial for early screening, tailored dietary management, and prevention of progressive liver injury in at-risk individuals. |
| Publish Date |
2025-12-22 07:43 |
| Citation |
Kalra S, Joshi S, Goyal MK, Goyal K, Singh B, Vuthaluru AR, Goyal O. Gluten’s silent strike: Unmasking its impact on liver health. World J Gastrointest Pathophysiol 2025; 16(4): 111957 |
| URL |
https://www.wjgnet.com/2150-5330/full/v16/i4/111957.htm |
| DOI |
https://dx.doi.org/10.4291/wjgp.v16.i4.111957 |
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