| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Autobiography |
| Article Title |
Biodegradable stent or balloon dilatation for benign oesophageal stricture: Pilot randomised controlled trial
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Anjan Dhar, Helen Close, Yirupaiahgari K Viswanath, Colin J Rees, Helen C Hancock, A Deepak Dwarakanath, Rebecca H Maier, Douglas Wilson and James M Mason |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Institute for Health Research under its Research (NIHR) |
PB-PG-1208-17025 |
| those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health |
|
|
| Corresponding Author |
Anjan Dhar, DM, MD, FRCPE, AGAF, Cert.Med.Ed, FHEA, Department of Gastroenterology, County Durham and Darlington NHS Foundation Trust, Cockton Hill Road, Co. Durham DL14 6AD, United Kingdom. anjan.dhar@cddft.nhs.uk |
| Key Words |
Benign oesophageal stricture; Biodegradable stent; Endoscopic balloon dilatation; Pilot study; Randomised controlled trial; Dysphagia |
| Core Tip |
Benign oesophageal strictures are managed by endoscopic dilatation using balloons or bougies, often requiring costly repeat procedures. Biodegradable stents do not usually require removal and may reduce the need for repeated endoscopy. This pilot multi-site randomized study demonstrates that stenting was associated with greater dysphagia, co-medication and adverse events. The oesophageal tract has somatic sensitivity and the process of the stent dissolving, possibly unevenly, might promote discomfort or reflux. Groups were comparable at baseline and findings are statistically significant but patient numbers were small. Rigorously conducted and adequately powered trials are needed before widespread adoption of this technology. |
| Publish Date |
2015-01-06 09:08 |
| Citation |
Dhar A, Close H, Viswanath YK, Rees CJ, Hancock HC, Dwarakanath AD, Maier RH, Wilson D, Mason JM. Biodegradable stent or balloon dilatation for benign oesophageal stricture: Pilot randomised controlled trial. World J Gastroenterol 2014; 20(48): 18199-18206 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i48/18199.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i48.18199 |
