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10/14/2025 7:42:35 AM | Browse: 23 | Download: 124
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 111971
Country China
Received
2025-07-18 03:14
Peer-Review Started
2025-07-18 03:14
To Make the First Decision
Return for Revision
2025-07-22 08:26
Revised
2025-08-06 07:22
Second Decision
2025-09-04 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-04 06:57
Articles in Press
2025-09-04 06:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
2025-09-05 03:18
Typeset the Manuscript
2025-09-25 01:34
Publish the Manuscript Online
2025-10-14 07:42
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type Retrospective Study
Article Title Predictive model based on magnetic resonance imaging for chemotherapy response in colorectal cancer patients with gene mutations
Manuscript Source Unsolicited Manuscript
All Author List Wen-Yan Kang, Wen-Ming Deng, Xiao-Qin Ye, Yi-Hong Zhong, Xiao-Jun Li, Ling-Ling Feng and De-Hong Luo
ORCID
Author(s) ORCID Number
Wen-Yan Kang http://orcid.org/0009-0008-1203-0289
Wen-Ming Deng http://orcid.org/0009-0007-1412-5938
Xiao-Qin Ye http://orcid.org/0009-0001-8102-8827
Yi-Hong Zhong http://orcid.org/0009-0008-5621-7897
Xiao-Jun Li http://orcid.org/0000-0002-4952-0184
Ling-Ling Feng http://orcid.org/0009-0005-7922-4596
De-Hong Luo http://orcid.org/0009-0001-7431-135X
Funding Agency and Grant Number
Funding Agency Grant Number
Shenzhen High-level Hospital Construction Fund
Corresponding Author De-Hong Luo, Department of Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 113 Baohe Avenue, Longgang District, Shenzhen 518116, Guangdong Province, China. luodehong2024@163.com
Key Words Colorectal cancer; RAS gene mutation; Multiparametric magnetic resonance imaging; Chemotherapy; Predictive model
Core Tip This study pioneers a multiparametric magnetic resonance imaging (MRI)-based predictive model tailored for colorectal cancer patients with gene mutations (e.g., KRAS, NRAS, BRAF) to evaluate chemotherapy efficacy. By integrating tumor differentiation, T2 signal intensity ratio, tumor-to-anal margin distance, and MRI-detected lymph node metastasis, the model achieved high accuracy (area under the receiver operating characteristic curve > 0.93) in both training and validation sets, offering a non-invasive tool for personalized treatment planning.
Publish Date 2025-10-14 07:42
Citation <p>Kang WY, Deng WM, Ye XQ, Zhong YH, Li XJ, Feng LL, Luo DH. Predictive model based on magnetic resonance imaging for chemotherapy response in colorectal cancer patients with gene mutations. <i>World J Gastrointest Oncol</i> 2025; 17(10): 111971</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i10/111971.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i10.111971
Full Article (PDF) WJGO-17-111971-with-cover.pdf
Manuscript File 111971_Auto_Edited_030525.docx
Answering Reviewers 111971-answering-reviewers.pdf
Audio Core Tip 111971-audio.mp3
Biostatistics Review Certificate 111971-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111971-conflict-of-interest-statement.pdf
Copyright License Agreement 111971-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111971-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111971-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111971-non-native-speakers.pdf
Peer-review Report 111971-peer-reviews.pdf
Scientific Misconduct Check 111971-scientific-misconduct-check.png
Scientific Editor Work List 111971-scientific-editor-work-list.pdf
CrossCheck Report 111971-crosscheck-report.pdf