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11/20/2025 7:56:48 AM | Browse: 10 | Download: 48
Publication Name World Journal of Gastroenterology
Manuscript ID 111976
Country China
Received
2025-07-24 09:06
Peer-Review Started
2025-07-24 09:07
To Make the First Decision
Return for Revision
2025-08-14 09:41
Revised
2025-08-26 05:11
Second Decision
2025-10-17 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-10-17 03:39
Articles in Press
2025-10-17 03:39
Publication Fee Transferred
2025-08-31 03:17
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-10 14:28
Publish the Manuscript Online
2025-11-20 07:56
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Retrospective Study
Article Title Peripheral blood lymphocyte subset deficiency in acute-on-chronic liver failure and reconstitution following liver transplantation
Manuscript Source Unsolicited Manuscript
All Author List Bo Peng, Zhi-Xin Li, Min Yang, Liu Kai, Xu-Yu Xiang, Ying Zhang, Jun-Hui Li, Peng-Peng Zhang, Quan Zhuang, Ke Cheng and Ying-Zi Ming
ORCID
Author(s) ORCID Number
Bo Peng http://orcid.org/0000-0003-4482-2885
Zhi-Xin Li http://orcid.org/0000-0003-3608-2266
Liu Kai http://orcid.org/0000-0003-3938-2993
Ke Cheng http://orcid.org/0000-0001-5304-8807
Ying-Zi Ming http://orcid.org/0009-0009-8878-3831
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China No. 82300857
Corresponding Author Ying-Zi Ming, Director, Professor, Transplantation Center, The Third Xiangya Hospital, Central South University, No. 138 Tongzipo Road, Changsha 410013, Hunan Province, China. mingyz_china@csu.edu.cn
Key Words Peripheral blood lymphocyte subset; Acute-on-chronic liver failure; Liver transplantation; Immune reconstitution; Postoperative prognosis
Core Tip Immune dysfunction is a hallmark characteristic of acute-on-chronic liver failure (ACLF). This study demonstrated that patients with ACLF exhibited a significant reduction in the level of peripheral blood lymphocyte subsets (PBLSs). Notably, natural killer (NK) cells may be associated with the progression of liver failure. Both NK and B cells have the potential to serve as biomarkers for immune recovery after liver transplantation. A thorough assessment of dynamic changes in PBLSs provided valuable insights into the evolving immune status of this population and supported the development of strategies for post-transplantation management.
Publish Date 2025-11-20 07:56
Citation <p>Peng B, Li ZX, Yang M, Kai L, Xiang XY, Zhang Y, Li JH, Zhang PP, Zhuang Q, Cheng K, Ming YZ. Peripheral blood lymphocyte subset deficiency in acute-on-chronic liver failure and reconstitution following liver transplantation. <i>World J Gastroenterol</i> 2025; 31(43): 111976</p>
URL https://www.wjgnet.com/1007-9327/full/v31/i43/111976.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i43.111976
Full Article (PDF) WJG-31-111976-with-cover.pdf
Manuscript File 111976_Auto_Edited_030309.docx
Answering Reviewers 111976-answering-reviewers.pdf
Audio Core Tip 111976-audio.mp3
Biostatistics Review Certificate 111976-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111976-conflict-of-interest-statement.pdf
Copyright License Agreement 111976-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111976-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111976-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111976-non-native-speakers.pdf
Supplementary Material 111976-supplementary-material.pdf
Peer-review Report 111976-peer-reviews.pdf
Scientific Misconduct Check 111976-scientific-misconduct-check.png
Scientific Editor Work List 111976-scientific-editor-work-list.pdf
CrossCheck Report 111976-crosscheck-report.pdf