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Articles Published Processes
3/6/2026 8:56:30 AM | Browse: 3 | Download: 13
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Received |
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2025-07-15 09:19 |
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Peer-Review Started |
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2025-07-15 09:19 |
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First Decision by Editorial Office Director |
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2025-08-08 08:22 |
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Return for Revision |
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2025-08-08 08:22 |
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Revised |
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2025-08-27 14:55 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-14 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-14 13:58 |
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Articles in Press |
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2025-11-14 13:58 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-03 00:36 |
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Publish the Manuscript Online |
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2026-03-06 08:56 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Minireviews |
| Article Title |
Role of biomarkers in pediatric sepsis: What evidence says?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Amit Agrawal, Dalwinder Janjua and Gaurav Jadon |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Amit Agrawal, Associate Professor, MD, Department of Pediatrics, Gandhi Medical College, Hamidia Hospital Campus, 49-B Indrapuri, B-Sector, Bhopal 462001, Madhya Pradesh, India. agrawaldramit@yahoo.co.in |
| Key Words |
Biomarker; C-reactive protein; Interleukin-8; Serum lactate; Procalcitonin; Sepsis' septic shock; Children |
| Core Tip |
Sepsis is common in hospitalized pediatric patients, leading to increased morbidity and mortality. Routine laboratory investigations cannot always identify the cause of diseases, and many biomarkers have been used to detect these infections. This review analyses the available evidence supporting the use of biomarkers, such as C-reactive protein, ferritin, lactate, procalcitonin, and tumor necrosis factor-alpha. The sensitivity of each marker varied in different studies, and no single biomarker can be used to identify all infections. Apart from the diagnosis, studies have assessed the role of these biomarkers in optimizing antibiotic therapy to promote early recovery. |
| Publish Date |
2026-03-06 08:56 |
| Citation |
Agrawal A, Janjua D, Jadon G. Role of biomarkers in pediatric sepsis: What evidence says? World J Clin Pediatr 2026; 15(1): 111999 |
| URL |
https://www.wjgnet.com/2219-2808/full/v15/i1/111999.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v15.i1.111999 |
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