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1/5/2026 6:55:13 AM | Browse: 3 | Download: 10
Publication Name World Journal of Clinical Cases
Manuscript ID 112021
Country Italy
Received
2025-07-16 02:34
Peer-Review Started
2025-07-16 02:34
First Decision by Editorial Office Director
2025-10-13 09:04
Return for Revision
2025-10-13 14:01
Revised
2025-10-13 16:07
Publication Fee Transferred
Second Decision by Editor
2025-12-15 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-16 01:58
Articles in Press
2025-12-16 01:58
Edit the Manuscript by Language Editor
2025-12-22 05:04
Typeset the Manuscript
2025-12-30 05:47
Publish the Manuscript Online
2026-01-05 06:55
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Discontinuation of advanced therapy in inflammatory bowel disease: Updated evidence, guidelines, and personalized decision-making one year later
Manuscript Source Unsolicited Manuscript
All Author List Salvatore Greco, Michele Campigotto and Nicolò Fabbri
ORCID
Author(s) ORCID Number
Salvatore Greco http://orcid.org/0000-0001-7334-0135
Michele Campigotto http://orcid.org/0000-0002-4702-3539
Nicolò Fabbri http://orcid.org/0000-0001-7039-3717
Funding Agency and Grant Number
Corresponding Author Salvatore Greco, MD, Department of Internal Medicine, Ospedale del Delta, AUSL Ferrara, Via valle Oppio 2, Lagosanto 44023, Ferrara, Italy. grcsvt@unife.it
Key Words Crohn’s disease; Ulcerative colitis; Inflammatory bowel disease; Biologic therapy; Discontinuation of therapy; Personalized medicine
Core Tip Discontinuation of advanced therapies in inflammatory bowel diseases remains a high-stakes decision, with relapse, immunogenicity, and long-term complications all weighing heavily. Despite updated international guidelines and emerging therapies, a personalized, closely monitored approach remains essential to ensure safe and effective treatment de-escalation in both Crohn’s disease and ulcerative colitis.
Publish Date 2026-01-05 06:55
Citation

Greco S, Campigotto M, Fabbri N. Discontinuation of advanced therapy in inflammatory bowel disease: Updated evidence, guidelines, and personalized decision-making one year later. World J Clin Cases 2026; 14(1): 112021

URL https://www.wjgnet.com/2307-8960/full/v14/i1/112021.htm
DOI https://dx.doi.org/10.12998/wjcc.v14.i1.112021
Full Article (PDF) WJCC-14-112021-with-cover.pdf
Manuscript File 112021_Auto_Edited_080346.docx
Answering Reviewers 112021-answering-reviewers.pdf
Audio Core Tip 112021-audio.mp3
Conflict-of-Interest Disclosure Form 112021-conflict-of-interest-statement.pdf
Copyright License Agreement 112021-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 112021-non-native-speakers.pdf
Peer-review Report 112021-peer-reviews.pdf
Scientific Misconduct Check 112021-scientific-misconduct-check.png
Scientific Editor Work List 112021-scientific-editor-work-list.pdf
CrossCheck Report 112021-crosscheck-report.pdf