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11/21/2025 7:06:13 AM | Browse: 2 | Download: 21
Publication Name World Journal of Clinical Oncology
Manuscript ID 112029
Country China
Received
2025-07-16 02:43
Peer-Review Started
2025-07-16 02:48
To Make the First Decision
Return for Revision
2025-08-04 07:44
Revised
2025-08-23 18:34
Second Decision
2025-10-27 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-10-27 08:04
Articles in Press
2025-10-27 08:04
Publication Fee Transferred
2025-08-30 15:13
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-14 09:02
Publish the Manuscript Online
2025-11-21 07:06
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Perioperative immunotherapy combined with standard therapy for human epidermal growth factor receptor 2-positive locally advanced gastric cancer: A case report
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Ting Ma, Guang-Yu Yao, Jian-Li Li, Xi-Cheng Wang and Yi Ba
ORCID
Author(s) ORCID Number
Xiao-Ting Ma http://orcid.org/0000-0003-1329-9761
Yi Ba http://orcid.org/0009-0007-9150-7972
Funding Agency and Grant Number
Funding Agency Grant Number
CAMS Innovation Fund for Medical Sciences (CIFMS) 2023-I2M-3-012
Corresponding Author Yi Ba, Department of Cancer Medical Center, Peking Union Medical College Hospital, Correspondence to: Yi Ba, E-mail: <email>bayi@pumch.cn</email>, Beijing 100730, China. bayi@pumch.cn
Key Words Human epidermal growth factor receptor 2; Immune checkpoint inhibitor; Gastric cancer; Neoadjuvant therapy; Trastuzumab; Case report
Core Tip The efficacy and safety of immune checkpoint inhibitors (ICIs) combination therapy in the perioperative period of human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) have not been confirmed by large-scale clinical studies. This study introduces a case of neoadjuvant treatment for HER2-positive GC using standard chemotherapy combined with anti-HER2 therapy, and systematically summarizes the current related research on chemotherapy combined with targeted therapy and ICI-based combined therapy. The efficacy of ICI combined therapy during the perioperative period still requires further confirmation through a phase III clinical trial.
Publish Date 2025-11-21 07:06
Citation <p>Ma XT, Yao GY, Li JL, Wang XC, Ba Y. Perioperative immunotherapy combined with standard therapy for human epidermal growth factor receptor 2-positive locally advanced gastric cancer: A case report. <i>World J Clin Oncol</i> 2025; 16(11): 112029</p>
URL https://www.wjgnet.com/2218-4333/full/v16/i11/112029.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i11.112029
Full Article (PDF) WJCO-16-112029-with-cover.pdf
CARE Checklist–2016 112029-CARE-Checklist-2016.pdf
Manuscript File 112029_Auto_Edited_034129.docx
Answering Reviewers 112029-answering-reviewers.pdf
Audio Core Tip 112029-audio.mp3
Conflict-of-Interest Disclosure Form 112029-conflict-of-interest-statement.pdf
Copyright License Agreement 112029-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 112029-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 112029-non-native-speakers.pdf
Peer-review Report 112029-peer-reviews.pdf
Scientific Misconduct Check 112029-scientific-misconduct-check.png
Scientific Editor Work List 112029-scientific-editor-work-list.pdf
CrossCheck Report 112029-crosscheck-report.pdf