| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Acute exercise-induced catecholaminergic responses after 16 weeks of community-based exercise training in early-stage breast cancer survivors
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Jeb F Struder, Aiden J Chauntry, Lauren C Bates-Fraser, Elizabeth P Harrell, Jordan T Lee, Chad W Wagoner, Stephanie A Sullivan, David B Bartlett, Hyman B Muss, Brian C Jensen, Claudio L Battaglini and Erik D Hanson |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Breast Cancer Research Foundation of New York, NY |
BCRF-17-112 |
| the National Cancer Institute’s National Research Service Award sponsored by the Lineberger Comprehensive Cancer Center at the University of North Carolina |
T32 CA116339 |
| the National Heart, Lung, and Blood Institute of the National Institutes of Health |
R01HL162805 and R01HL157187 |
|
| Corresponding Author |
Erik D Hanson, Associate Professor, PhD, Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Campus Box #8700, Chapel Hill, NC 27599, United States. edhanson@email.unc.edu |
| Key Words |
Autonomic function; Breast neoplasms; Cancer survivorship; Cardiovascular stress response; Catecholamines; Exercise therapy; Sympathetic nervous system |
| Core Tip |
Exercise training partially restored immune cell responses previously diminished within untrained breast cancer survivors (BCS) immediately post-exercise. Epinephrine and norepinephrine are exercise-responsive and regulate immune cell function, suggesting a role in this training-induced restoration. Acute exercise induces similar BCS catecholaminergic attenuation; however, it is unclear whether this is sustained post-training. In this study, we aimed to compare acute exercise-induced catecholaminergic responses between BCS and non-cancer controls (CON) before and after a training intervention. BCS and CON presented with similar exercise-induced catecholaminergic responses regardless of training, suggesting the immune cell revival previously observed may be regulated by alternative mechanisms. |
| Publish Date |
2026-01-20 09:06 |
| Citation |
Struder JF, Chauntry AJ, Bates-Fraser LC, Harrell EP, Lee JT, Wagoner CW, Sullivan SA, Bartlett DB, Muss HB, Jensen BC, Battaglini CL, Hanson ED. Acute exercise-induced catecholaminergic responses after 16 weeks of community-based exercise training in early-stage breast cancer survivors. World J Clin Oncol 2026; 17(1): 112039 |
| URL |
https://www.wjgnet.com/2218-4333/full/v17/i1/112039.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v17.i1.112039 |
