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Articles Published Processes
12/31/2025 5:47:44 AM | Browse: 82 | Download: 218
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Received |
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2025-07-17 04:06 |
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Peer-Review Started |
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2025-07-17 04:06 |
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First Decision by Editorial Office Director |
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2025-09-04 06:43 |
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Return for Revision |
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2025-09-04 06:43 |
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Revised |
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2025-09-05 00:11 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-12 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-12 09:02 |
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Articles in Press |
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2025-11-12 09:02 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-19 02:38 |
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Publish the Manuscript Online |
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2025-12-31 05:47 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Editorial |
| Article Title |
Unlocking the silent signals: Motor kinematics as a new frontier in early detection of mild cognitive impairment
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Takahiko Nagamine |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Takahiko Nagamine, MD, PhD, Professor, Psychiatric Internal Medicine, Sunlight Brain Research Center, 4-13-18 Jiyugaoka, Hofu 7470066, Yamaguchi, Japan. anagamine@yahoo.co.jp |
| Key Words |
Mild cognitive impairment; Early detection; Motor kinematics; Gait analysis; Handwriting analysis; Digital biomarkers; Machine learning |
| Core Tip |
This study proposes a paradigm shift in mild cognitive impairment screening, moving from subjective cognitive tests to objective, quantifiable measures of gait and handwriting kinematics. This novel approach uses readily observable behaviors and non-invasive technology (like digital pens) to circumvent barriers of traditional neuropsychological assessments, such as language dependency and cultural bias. By measuring motor kinematics, which capture the real-world effect of cognitive-motor changes, the method offers ecological validity and reflects functional status, distinguishing it from biomarkers focused only on pathology. The integration of gross and fine motor abilities provides a scalable and accessible foundation for early, proactive mild cognitive impairment detection, paving the way for better intervention. |
| Publish Date |
2025-12-31 05:47 |
| Citation |
Nagamine T. Unlocking the silent signals: Motor kinematics as a new frontier in early detection of mild cognitive impairment. World J Psychiatry 2026; 16(1): 112073 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i1/112073.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i1.112073 |
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