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Articles Published Processes
3/6/2026 8:56:27 AM | Browse: 4 | Download: 28
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Received |
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2025-07-17 01:43 |
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Peer-Review Started |
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2025-07-17 01:43 |
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First Decision by Editorial Office Director |
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2025-07-28 08:31 |
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Return for Revision |
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2025-07-28 08:31 |
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Revised |
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2025-08-09 16:54 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-28 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-28 08:12 |
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Articles in Press |
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2025-10-28 08:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-22 09:02 |
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Publish the Manuscript Online |
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2026-03-06 08:56 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Comparison of Bilirubin Albumin Ratio and Total Serum Bilirubin for Predicting Neurological Dysfunction in Newborns: Meta Analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Nabeel Ahmad, Uzair Ahmed, Ghulam Mohy Ud Din, Mavia Habib, Muhammad Shaheer Luqman, Muhammad Talha, Muneeb Saifullah and Ikra Rana |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ikra Rana, MD, Department of Medicine, International School of Medicine, International University of Kyrgyzstan, 6 Street, Bishkek 720074, Kyrgyzstan. ikrarana100@gmail.com |
| Key Words |
Neonatal hyperbilirubinemia; Bilirubin-induced neurologic dysfunction; Total serum bilirubin; Bilirubin-albumin ratio; Diagnostic accuracy; Meta-analysis; Kernicterus; Neonatal jaundice; Albumin binding; Neurotoxicity |
| Core Tip |
Bilirubin-induced neurologic dysfunction (BIND) remains a preventable cause of neonatal brain injury, yet early risk stratification is challenging. We conducted a meta-analysis of observational studies using clinical criteria to diagnose BIND and found that elevated serum bilirubin/albumin (B/A) ratio is significantly associated with increased risk of BIND. This association remained robust across subgroup and meta-regression analyses. Our findings support the B/A ratio as a simple, accessible biomarker that may improve clinical prediction of BIND and guide early intervention in jaundiced neonates. |
| Publish Date |
2026-03-06 08:56 |
| Citation |
Ahmad N, Ahmed U, Mohy Ud Din G, Habib M, Luqman MS, Talha M, Saifullah M, Rana I. Comparison of Bilirubin Albumin Ratio and Total Serum Bilirubin for Predicting Neurological Dysfunction in Newborns: Meta Analysis. World J Clin Pediatr 2026; 15(1): 112088 |
| URL |
https://www.wjgnet.com/2219-2808/full/v15/i1/112088.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v15.i1.112088 |
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