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10/27/2025 10:57:51 AM | Browse: 139 | Download: 185
Publication Name World Journal of Hepatology
Manuscript ID 112104
Country China
Received
2025-07-17 12:24
Peer-Review Started
2025-07-17 12:25
First Decision by Editorial Office Director
2025-08-28 09:27
Return for Revision
2025-08-28 09:27
Revised
2025-08-30 08:30
Publication Fee Transferred
Second Decision by Editor
2025-09-15 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-09-17 10:34
Articles in Press
2025-09-17 10:34
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-17 06:21
Publish the Manuscript Online
2025-10-27 10:57
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General & Internal
Manuscript Type Letter to the Editor
Article Title Predicting steroid response in acute alcohol-associated hepatitis: Beyond biomarkers of alcohol consumption
Manuscript Source Invited Manuscript
All Author List Jin-Wei Zhang
ORCID
Author(s) ORCID Number
Jin-Wei Zhang http://orcid.org/0000-0001-8683-509X
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China No. 82170406
National Natural Science Foundation of China No. 81970238
Corresponding Author Jin-Wei Zhang, PhD, Professor, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, No. 345 Lingling Road, Shanghai 200032, China. jinweizhang@sioc.ac.cn
Key Words Acute alcohol-associated hepatitis; Steroid therapy; Treatment response; Biomarkers; Liver transplantation; Phosphatidylethanol
Core Tip This manuscript offers a thorough analysis of Sabatose et al's study exploring predictors of steroid response in acute alcohol-associated hepatitis (AAH). The study examines the role of alcohol consumption biomarkers (such as phosphatidylethanol) and clinical factors, revealing that age, pre-steroid albumin, and bilirubin levels-rather than alcohol-related markers-are key predictors of non-response. The identification of poorer outcomes in non-responders, coupled with insights into limitations and future research directions, provides valuable guidance for clinical decision-making and the development of improved strategies for AAH management.
Publish Date 2025-10-27 10:57
Citation

Zhang JW. Predicting steroid response in acute alcohol-associated hepatitis: Beyond biomarkers of alcohol consumption. World J Hepatol 2025; 17(10): 112104

URL https://www.wjgnet.com/1948-5182/full/v17/i10/112104.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i10.112104
Full Article (PDF) WJH-17-112104-with-cover.pdf
Manuscript File 112104_Auto_Edited_093315.docx
Answering Reviewers 112104-answering-reviewers.pdf
Audio Core Tip 112104-audio.mp3
Conflict-of-Interest Disclosure Form 112104-conflict-of-interest-statement.pdf
Copyright License Agreement 112104-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 112104-non-native-speakers.pdf
Peer-review Report 112104-peer-reviews.pdf
Scientific Misconduct Check 112104-scientific-misconduct-check.png
Scientific Editor Work List 112104-scientific-editor-work-list.pdf
CrossCheck Report 112104-crosscheck-report.pdf