| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Reduced recurrence rate with a targeted approach in uncomplicated appendicitis treated with endoscopic direct vs retrograde therapy
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun Cai, Yang-Bor Lu, Yang Lv, Xiao-Juan Zhan, Ting Li, Guang Yang, Yu-Tong Ma, Jian-Zhen Ren, Bo Li, Heng Yu, Su-Huan Liao, Yi-Tian Guo, Qiu-Ping Qiu, Xiao-Ping Hong, Long-Bin Huang, Yu Zhang and Si-Lin Huang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Guangdong Province Clinical Teaching Base Teaching Reform Research Project |
2021JD086 |
|
| Corresponding Author |
Si-Lin Huang, Associate Chief Physician, Head, MD, Department of Gastroenterology, South China Hospital, Medical School, Shenzhen University, No. 1 Fuxin Road, Longgang District, Shenzhen 518116, Guangdong Province, China. silinhuang@szu.edu.cn |
| Key Words |
Appendicography; Appendicolith; Appendicoscope; Diagnosis; Endoscopic direct appendicitis therapy; Endoscopic retrograde appendicitis therapy; Fecalith; Negative appendectomy; Uncomplicated appendicitis |
| Core Tip |
Endoscopic direct appendicitis therapy (EDAT) shows clear clinical advantages over endoscopic retrograde appendicitis therapy (ERAT) in the management of uncomplicated appendicitis. EDAT achieved significantly higher intervention success and lower recurrence rates, including in patients with appendicoliths, a subgroup at a high risk of antibiotic treatment failure. It also shortens hospital stay and stent replacement, improving procedural efficiency. As the first head-to-head comparison of EDAT and ERAT, this study provided novel evidence supporting EDAT as a more effective, minimally invasive option, with important implications for evolving non-surgical management strategies. |
| Publish Date |
2025-11-13 06:51 |
| Citation |
<p>Cai J, Lu YB, Lv Y, Zhan XJ, Li T, Yang G, Ma YT, Ren JZ, Li B, Yu H, Liao SH, Guo YT, Qiu QP, Hong XP, Huang LB, Zhang Y, Huang SL. Reduced recurrence rate with a targeted approach in uncomplicated appendicitis treated with endoscopic direct vs retrograde therapy. <i>World J Gastroenterol</i> 2025; 31(42): 112106</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i42/112106.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i42.112106 |
