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Articles Published Processes
12/31/2025 5:47:39 AM | Browse: 3 | Download: 15
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Received |
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2025-08-15 08:27 |
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Peer-Review Started |
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2025-08-15 08:27 |
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First Decision by Editorial Office Director |
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2025-09-04 06:46 |
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Return for Revision |
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2025-09-04 06:46 |
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Revised |
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2025-09-15 13:23 |
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Publication Fee Transferred |
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2025-09-19 08:46 |
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Second Decision by Editor |
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2025-10-28 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-28 06:43 |
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Articles in Press |
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2025-10-28 06:43 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-18 12:18 |
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Publish the Manuscript Online |
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2025-12-31 05:47 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Retrospective Study |
| Article Title |
Clinical efficacy and effects on hypothalamic-pituitary-adrenal axis function of proscar combined with selective serotonin reuptake inhibitor in post-stroke depression
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ming-Yang Xu, Yi Lu, Guo-Mei Shi, Jun Yao, Chun-Qin Ding and Ru-Juan Zhou |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Open Project of Jiangsu Province Key Laboratory of Integrated Traditional Chinese and Western Medicine for the Prevention and Treatment of Geriatric Diseases |
202232 |
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| Corresponding Author |
Chun-Qin Ding, Associate Chief Physician, Department of Neurology, Yangzhou University Affiliated Taixing Hospital, No. 1 Changzheng Road, Taixing 225400, Jiangsu Province, China. myxu1986@foxmail.com |
| Key Words |
Free San; Selective serotonin reuptake inhibitor; Paroxetine; Post-stroke depression; Hypothalamic-pituitary-adrenal axis |
| Core Tip |
Combining selective serotonin reuptake inhibitors with the traditional Chinese medicine Free San significantly improves the treatment efficacy for post-stroke depression. The novel combination therapy not only alleviated depressive symptoms more effectively than selective serotonin reuptake inhibitors alone but also normalized hypothalamic-pituitary-adrenal axis dysfunction, as evidenced by reduced cortisol and corticotropin-releasing hormone levels. This approach has a good safety profile, suggesting that it is a promising integrative treatment strategy for post-stroke depression. |
| Publish Date |
2025-12-31 05:47 |
| Citation |
Xu MY, Lu Y, Shi GM, Yao J, Ding CQ, Zhou RJ. Clinical efficacy and effects on hypothalamic-pituitary-adrenal axis function of proscar combined with selective serotonin reuptake inhibitor in post-stroke depression. World J Psychiatry 2026; 16(1): 112139 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i1/112139.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i1.112139 |
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