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11/21/2025 3:54:19 AM | Browse: 3 | Download: 17
Publication Name World Journal of Clinical Cases
Manuscript ID 112160
Country United States
Received
2025-07-21 06:49
Peer-Review Started
2025-07-21 06:50
To Make the First Decision
Return for Revision
2025-08-14 12:35
Revised
2025-08-16 01:02
Second Decision
2025-10-23 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-10-23 07:16
Articles in Press
2025-10-23 07:16
Publication Fee Transferred
2025-08-24 14:11
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-14 01:54
Publish the Manuscript Online
2025-11-21 03:54
ISSN 2307-8960 (online)
Open Access Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Multidisciplinary Sciences
Manuscript Type Case Report
Article Title Squamous cell carcinoma of unknown primary in the pelvis after complete remission following chemoradiotherapy: A case report
Manuscript Source Unsolicited Manuscript
All Author List Anupam K Gupta and Harsha Polavarapu
ORCID
Author(s) ORCID Number
Anupam K Gupta http://orcid.org/0009-0009-1875-8024
Funding Agency and Grant Number
Corresponding Author Anupam K Gupta, Department of General Surgery, SSM Health, 1 Good Samaritan Way, Mt Vernon, IL 62864, Mt Vernon, IL 62864, United States. dranupamkumargupta@gmail.com
Key Words Squamous cell carcinoma; Cancer of unknown primary; Pelvic malignancy; Chemoradiotherapy; Human papillomavirus negative; p40 positive; Pelvic floor tumor; Case report
Core Tip This case report describes an elderly woman with pelvic squamous cell carcinoma of unknown primary (CUP), an entity accounting for less than 1% of CUP cases. A comprehensive diagnostic workup ruled out common primaries, and multidisciplinary evaluation led to chemoradiotherapy with 5-fluorouracil and mitomycin-C plus radiotherapy. The patient achieved complete remission for 12 months with improved functional status. This report emphasizes the value of imaging, pathology, and individualized multidisciplinary management in achieving durable remission in rare pelvic squamous CUP.
Publish Date 2025-11-21 03:54
Citation <p>Gupta AK, Polavarapu H. Squamous cell carcinoma of unknown primary in the pelvis after complete remission following chemoradiotherapy: A case report. <i>World J Clin Cases</i> 2025; 13(33): 112160</p>
URL https://www.wjgnet.com/2307-8960/full/v13/i33/112160.htm
DOI https://dx.doi.org/10.12998/wjcc.v13.i33.112160
Full Article (PDF) WJCC-13-112160-with-cover.pdf
CARE Checklist–2016 112160-CARE-Checklist-2016.pdf
Manuscript File 112160_Auto_Edited_034625.docx
Answering Reviewers 112160-answering-reviewers.pdf
Audio Core Tip 112160-audio.m4a
Conflict-of-Interest Disclosure Form 112160-conflict-of-interest-statement.pdf
Copyright License Agreement 112160-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 112160-informed-consent-statement.pdf
Peer-review Report 112160-peer-reviews.pdf
Scientific Misconduct Check 112160-scientific-misconduct-check.png
Scientific Editor Work List 112160-scientific-editor-work-list.pdf
CrossCheck Report 112160-crosscheck-report.pdf