BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
1/9/2026 9:47:33 AM | Browse: 3 | Download: 15
 |
Received |
|
2025-07-23 05:49 |
|
Peer-Review Started |
|
2025-07-23 05:50 |
|
First Decision by Editorial Office Director |
|
2025-08-25 07:45 |
|
Return for Revision |
|
2025-08-25 07:45 |
|
Revised |
|
2025-09-04 13:29 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2025-11-14 02:42 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-11-14 14:20 |
|
Articles in Press |
|
2025-11-14 14:20 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-12-30 03:54 |
|
Publish the Manuscript Online |
|
2026-01-09 09:47 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Basic Study |
| Article Title |
Novel use of bisphosphonates to improve surgical outcomes in experimental bone tuberculosis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Veronika V Petukhova, Alexander Yu Mushkin, Alexey S Maletin, Marine Z Dogonadze, Natalia V Zabolotnykh, Marina E Dyakova, Dilyara S Esmedlyaeva, Tatiana I Vinogradova and Mikhail M Kostik |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Russian Science Foundation |
24-15-00185 |
|
| Corresponding Author |
Mikhail M Kostik, MD, PhD, Professor, Hospital Pediatrics, Saint Petersburg State Pediatric Medical University, Lytovskaya 2, Saint Petersburg 194100, Russia. kost-mikhail@yandex.ru |
| Key Words |
Tuberculosis; Bone and joint tuberculosis; Pamidronate; Bisphosphonates; Bone regeneration; Bone grafting; Bone resorption |
| Core Tip |
A single intravenous dose of pamidronate significantly enhances bone regeneration after surgical treatment of experimental tuberculous osteitis. Pamidronate effectively inhibits early implant resorption, increases osteoblastic activity, and promotes prolonged osteogenesis, showing compatibility and safety when combined with antituberculosis therapy. This finding suggests that bisphosphonates may be a promising adjunctive therapeutic strategy for enhancing clinical outcomes in patients undergoing skeletal tuberculosis surgery. |
| Publish Date |
2026-01-09 09:47 |
| Citation |
Petukhova VV, Mushkin AY, Maletin AS, Dogonadze MZ, Zabolotnykh NV, Dyakova ME, Esmedlyaeva DS, Vinogradova TI, Kostik MM. Novel use of bisphosphonates to improve surgical outcomes in experimental bone tuberculosis. World J Orthop 2026; 17(1): 112262 |
| URL |
https://www.wjgnet.com/2218-5836/full/v17/i1/112262.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v17.i1.112262 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
