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2/28/2026 7:48:44 AM | Browse: 2 | Download: 17
Publication Name World Journal of Critical Care Medicine
Manuscript ID 112265
Country Russia
Received
2025-07-23 04:46
Peer-Review Started
2025-07-23 04:46
First Decision by Editorial Office Director
2025-08-27 07:50
Return for Revision
2025-08-27 07:50
Revised
2025-09-10 04:12
Publication Fee Transferred
Second Decision by Editor
2025-11-27 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-27 08:35
Articles in Press
2025-11-27 08:35
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-09 01:01
Publish the Manuscript Online
2026-02-28 07:48
ISSN 2220-3141(online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Retrospective Cohort Study
Article Title Death in patients with immune-mediated inflammatory diseases in the intensive care unit: First week data
Manuscript Source Invited Manuscript
All Author List Ilia S Avrusin, Natalia N Abramova, Liudmila A Firsova, Yury S Aleksandrovich, Dmitry O Ivanov and Mikhail M Kostik
ORCID
Author(s) ORCID Number
Ilia S Avrusin http://orcid.org/0000-0002-4919-0939
Liudmila A Firsova http://orcid.org/0000-0001-5024-1417
Yury S Aleksandrovich http://orcid.org/0000-0002-2131-4813
Dmitry O Ivanov http://orcid.org/0000-0002-0060-4168
Mikhail M Kostik http://orcid.org/0000-0002-1180-8086
Funding Agency and Grant Number
Corresponding Author Mikhail M Kostik, MD, PhD, Professor, Hospital Pediatrics, Saint Petersburg State Pediatric Medical University, Lytovskaya 2, Saint Petersburg 194100, Sankt-Peterburg, Russia. kost-mikhail@yandex.ru
Key Words Intensive care unit; Systemic inflammation; Systemic rheumatic diseases; Sepsis; Multisystem inflammatory syndrome associated with coronavirus disease 2019 in children; Children
Core Tip Systemic immune-mediated inflammatory diseases can be severe in both course and complications, quite often requiring intensive care unit admission and, in some cases, leading to death. For such patients, careful observation and dynamic monitoring of their condition, along with risk assessment, is critical. The risk factors for a lethal outcome during the first week of intensive care unit stay included signs of hemophagocytosis, progressive decline in the Glasgow Coma Scale, increasing Sequential Organ Failure Assessment scores, and persistent high C-reactive protein levels. Monitoring of these parameters may help to timely identify the patients at high risk of lethal outcome, allowing for the prompt prescription of appropriate treatment.
Publish Date 2026-02-28 07:48
Citation

Avrusin IS, Abramova NN, Firsova LA, Aleksandrovich YS, Ivanov DO, Kostik MM. Death in patients with immune-mediated inflammatory diseases in the intensive care unit: First week data. World J Crit Care Med 2026; 15(1): 112265

URL https://www.wjgnet.com/2220-3141/full/v15/i1/112265.htm
DOI https://dx.doi.org/10.5492/wjccm.v15.i1.112265
Full Article (PDF) WJCCM-15-112265-with-cover.pdf
STROBE Statement 112265-STROBE-statement.pdf
Manuscript File 112265_Auto_Edited_082043.docx
Answering Reviewers 112265-answering-reviewers.pdf
Audio Core Tip 112265-audio.m4a
Biostatistics Review Certificate 112265-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 112265-conflict-of-interest-statement.pdf
Copyright License Agreement 112265-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 112265-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 112265-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 112265-non-native-speakers.pdf
Supplementary Material 112265-supplementary-material.pdf
Peer-review Report 112265-peer-reviews.pdf
Scientific Misconduct Check 112265-scientific-misconduct-check.png
Scientific Editor Work List 112265-scientific-editor-work-list.pdf
CrossCheck Report 112265-crosscheck-report.pdf