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9/25/2025 3:33:09 AM | Browse: 87 | Download: 53
Publication Name World Journal of Gastroenterology
Manuscript ID 112298
Country South Korea
Received
2025-07-23 04:17
Peer-Review Started
2025-07-23 04:18
To Make the First Decision
Return for Revision
2025-08-14 09:37
Revised
2025-08-23 01:25
Second Decision
2025-09-04 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-04 03:22
Articles in Press
2025-09-04 03:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-22 02:09
Publish the Manuscript Online
2025-09-25 03:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Unraveling the gut-liver axis in autoimmune liver disease overlap syndrome: A multi-omics perspective
Manuscript Source Unsolicited Manuscript
All Author List Eguono D Akpoveta, Uchenna E Okpete and Haewon Byeon
ORCID
Author(s) ORCID Number
Eguono D Akpoveta http://orcid.org/0009-0000-9058-0448
Uchenna E Okpete http://orcid.org/0000-0003-3803-4583
Haewon Byeon http://orcid.org/0000-0002-3363-390X
Funding Agency and Grant Number
Funding Agency Grant Number
Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education No. RS-2023-00237287
Corresponding Author Haewon Byeon, Associate Professor, Director, PhD, Worker’s Care and Digital Health Lab, Department of Future Technology, Korea University of Technology and Education, 1600, Chungjeol-ro, Cheonan 31253, Chungcheongnam-do, South Korea. bhwpuma@naver.com
Key Words Gut microbiota; Autoimmune liver disease; Serum metabolites; Microbiome-metabolite interactions; Primary biliary cholangitis; Autoimmune hepatitis; Multi-omics analysis; Gut-liver axis
Core Tip Autoimmune liver disease overlap syndrome, involving features of both primary biliary cholangitis and autoimmune hepatitis, poses diagnostic and therapeutic challenges due to its complex pathophysiology. This letter highlights recent evidence linking gut microbiota alterations and serum metabolite changes to liver function in affected patients. The integration of microbial and metabolic data revealed novel interaction networks that may serve as biomarkers for disease differentiation and progression.
Publish Date 2025-09-25 03:33
Citation <p>Akpoveta ED, Okpete UE, Byeon H. Unraveling the gut-liver axis in autoimmune liver disease overlap syndrome: A multi-omics perspective. <i>World J Gastroenterol</i> 2025; 31(37): 112298</p>
URL https://www.wjgnet.com/1007-9327/full/v31/i37/112298.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i37.112298
Full Article (PDF) WJG-31-112298-with-cover.pdf
Manuscript File 112298_Auto_Edited_025924.docx
Answering Reviewers 112298-answering-reviewers.pdf
Audio Core Tip 112298-audio.mp3
Conflict-of-Interest Disclosure Form 112298-conflict-of-interest-statement.pdf
Copyright License Agreement 112298-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 112298-non-native-speakers.pdf
Peer-review Report 112298-peer-reviews.pdf
Scientific Misconduct Check 112298-scientific-misconduct-check.png
Scientific Editor Work List 112298-scientific-editor-work-list.pdf
CrossCheck Report 112298-crosscheck-report.pdf