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Articles Published Processes
11/27/2025 7:53:57 AM | Browse: 0 | Download: 0
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Received |
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2025-07-24 07:46 |
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Peer-Review Started |
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2025-07-24 07:47 |
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To Make the First Decision |
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Return for Revision |
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2025-08-01 09:10 |
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Revised |
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2025-08-14 05:08 |
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Second Decision |
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2025-10-20 02:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-10-20 03:51 |
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Articles in Press |
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2025-10-20 03:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-14 05:39 |
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Publish the Manuscript Online |
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2025-11-27 07:53 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Beyond bones: Revisiting the role of vitamin D in chronic liver disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rodrigo Guerrero-Guerrero, Osvely Mendez-Guerrero, Anaisa Carranza-Carrasco, Farid Tejeda, Astrid Ardon-Lopez and Nalu Navarro-Alvarez |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Nalu Navarro-Alvarez, Assistant Professor, MD, PhD, Department of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, 15 Vasco de Quiroga, Mexico City 14080, Mexico. nalu.navarroa@incmnsz.mx |
| Key Words |
Vitamin D; Vitamin D receptor; Fibrosis; Inflammation; Immune response; Vitamin D deficiency; Chronic liver diseases |
| Core Tip |
Vitamin D plays diverse roles in chronic liver disease beyond bone health, including modulation of fibrosis, immune responses, bile acid metabolism, and oxidative stress via vitamin D receptor signaling. Deficiency is common across liver disease etiologies and linked to worse outcomes. Although preclinical data are promising, clinical trials have yielded inconsistent results. This review summarizes the mechanistic and clinical evidence for vitamin D in autoimmune, viral, alcoholic, and metabolic liver diseases, emphasizing its potential as a modifiable factor and the need to define patient subgroups most likely to benefit from supplementation. |
| Publish Date |
2025-11-27 07:53 |
| Citation |
<p>Guerrero-Guerrero R, Mendez-Guerrero O, Carranza-Carrasco A, Tejeda F, Ardon-Lopez A, Navarro-Alvarez N. Beyond bones: Revisiting the role of vitamin D in chronic liver disease. <i>World J Hepatol</i> 2025; 17(11): 112315</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i11/112315.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i11.112315 |
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