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Articles Published Processes
2/11/2026 3:41:43 AM | Browse: 1 | Download: 11
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Received |
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2025-07-24 07:16 |
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Peer-Review Started |
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2025-07-24 07:16 |
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First Decision by Editorial Office Director |
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2025-09-03 06:57 |
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Return for Revision |
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2025-09-03 07:18 |
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Revised |
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2025-09-08 19:07 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-24 02:49 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-24 08:57 |
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Articles in Press |
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2025-11-24 08:57 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-22 08:55 |
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Publish the Manuscript Online |
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2026-02-11 03:41 |
| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Editorial |
| Article Title |
Ileal bile acid transporter inhibitors for chronic constipation in the elderly
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Payila Satya Raghava Aneesh, Venkatesh Vaithiyam, Ravi Teja Reddy, Ashok Dalal and Sanjeev Sachdeva |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Venkatesh Vaithiyam, Assistant Professor, Department of Gastroenterology, Govind Ballabh Pant Institute of Post Graduate Medical Education and Research, New Delhi 110002, Delhi, India. venkateshvaithiyam172@gmail.com |
| Key Words |
Ileal bile acid transporter; Elobixibat; Chronic constipation; Elderly; Colonic motility |
| Core Tip |
This article offers a critical review of a recently published study on elobixibat in the treatment of chronic constipation in the elderly. The therapeutic arsenal against chronic constipation is expanding with new drugs and approaches. Elobixibat is a potent and selective inhibitor of the ileal bile acid transporter. It increases the colonic bile acid pool, which enhances colonic motility and secretion. Elobixibat improves bowel movements, stool consistency, and quality of life. Elobixibat is generally well-tolerated and effective in the elderly, as well as in patients with renal failure, heart failure, and Parkinson’s disease suffering from chronic constipation. |
| Publish Date |
2026-02-11 03:41 |
| Citation |
Aneesh PSR, Vaithiyam V, Reddy RT, Dalal A, Sachdeva S. Ileal bile acid transporter inhibitors for chronic constipation in the elderly. World J Gastrointest Pharmacol Ther 2026; 17(1): 112327 |
| URL |
https://www.wjgnet.com/2150-5349/full/v17/i1/112327.htm |
| DOI |
https://dx.doi.org/10.4292/wjgpt.v17.i1.112327 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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