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Articles Published Processes
11/14/2025 12:56:20 AM | Browse: 3 | Download: 43
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Received |
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2025-08-01 13:37 |
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Peer-Review Started |
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2025-08-01 13:38 |
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To Make the First Decision |
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Return for Revision |
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2025-08-15 08:50 |
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Revised |
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2025-08-29 07:24 |
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Second Decision |
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2025-10-17 02:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-10-17 06:37 |
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Articles in Press |
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2025-10-17 06:37 |
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Publication Fee Transferred |
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2025-09-09 07:15 |
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Edit the Manuscript by Language Editor |
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2025-10-21 20:57 |
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Typeset the Manuscript |
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2025-11-04 08:48 |
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Publish the Manuscript Online |
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2025-11-14 00:56 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Report |
| Article Title |
Patient-derived organoids promoting the personalized treatment in pancreatic neuroendocrine tumor with liver metastases: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Min Yang, Wei Sun, Yong-Gang He, Xue-Hui Peng, Nan You, Yi-Chen Tang, Lu Zheng and Xiao-Bing Huang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chongqing Natural Science Foundation General Project |
CSTB2023NSCQ-MSX0182 and CSTB2023NSCQ-MSX0252 |
| Clinical Research Special Project of The Second Affiliated Hospital of Army Medical University |
2024 F022 |
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| Corresponding Author |
Xiao-Bing Huang, Chief Physician, Department of Hepatobiliary, The Second Affiliated Hospital of Army Medical University, No.83 Xinqiaozheng Street, Shapingba District, Chongqing 400037, China. 13372618116@tmmu.edu.cn |
| Key Words |
Pancreatic neuroendocrine tumors; Liver metastases; Patient-derived organoids; Personalized treatment; Transarterial chemoembolization; Case report |
| Core Tip |
Patient-derived organoids (PDOs) show great potential for predicting treatment response in various cancer types. Although gastroenteropancreatic neuroendocrine neoplasm organoids can retain the pathohistological and functional phenotypes of parental tumors, their roles in the prediction of clinical outcomes are not presented. Here, we first reported a case of pancreatic neuroendocrine tumor with liver metastases who successfully received surgery after personalized treatment guided by PDO-based drug sensitivity testing and achieved a good prognosis. Therefore, for the individual pancreatic neuroendocrine tumor patients with liver metastases, PDOs contribute to screening effective chemotherapy drugs to facilitate the personalized treatment, providing opportunities for surgical resection and improvement of survival outcomes. |
| Publish Date |
2025-11-14 00:56 |
| Citation |
<p>Yang XM, Sun W, He YG, Peng XH, You N, Tang YC, Zheng L, Huang XB. Patient-derived organoids promoting the personalized treatment in pancreatic neuroendocrine tumor with liver metastases: A case report. <i>World J Gastrointest Oncol</i> 2025; 17(11): 112385</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i11/112385.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i11.112385 |
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