Publication Name	World Journal of Stem Cells
Manuscript ID	112397
Country	South Korea

Received	2025-07-28 04:40
Peer-Review Started	2025-07-28 04:40
To Make the First Decision
Return for Revision	2025-08-14 07:02
Revised	2025-08-22 11:19
Second Decision	2025-10-09 01:12
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-10-09 07:17
Articles in Press	2025-10-09 07:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-10-17 08:33
Publish the Manuscript Online	2025-10-25 01:11

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cell & Tissue Engineering
Manuscript Type	Editorial
Article Title	Engineering ligament tissues: Synergistic power of aligned nanofibers and cyclic stretch
Manuscript Source	Invited Manuscript
All Author List	Atharva A Mahajan, Ramya Lakshmi Rajendran, Prakash Gangadaran and Byeong-Cheol Ahn
ORCID	Author(s) ORCID Number Atharva A Mahajan http://orcid.org/0000-0002-8099-8127 Ramya Lakshmi Rajendran http://orcid.org/0000-0001-6987-0854 Prakash Gangadaran http://orcid.org/0000-0002-0658-4604 Byeong-Cheol Ahn http://orcid.org/0000-0001-7700-3929
Funding Agency and Grant Number	Funding Agency Grant Number Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education NRF-2022R1I1A1A01068652
Corresponding Author	Byeong-Cheol Ahn, Department of Nuclear Medicine, School of Medicine, Kyungpook National University, No. 680 Gukchaebosang ro, Jung gu, Daegu 41944, South Korea. abc2000@knu.ac.kr
Key Words	Tissue engineering; Mesenchymal stem cells; Nanofiber scaffold; Cyclic strain; Tenogenesis; Rho-associated protein kinase inhibition
Core Tip	Yang et al demonstrate that aligned nanofiber scaffolds combined with cyclic strain synergistically promote tenogenic differentiation of mesenchymal stem cells. This biomimetic strategy mimics native ligament cues and remains effective even under Rho-associated protein kinase inhibition, offering a promising, clinically translatable approach for engineering functional ligament grafts in regenerative medicine.
Publish Date	2025-10-25 01:11
Citation	<p>Mahajan AA, Rajendran RL, Gangadaran P, Ahn BC. Engineering ligament tissues: Synergistic power of aligned nanofibers and cyclic stretch. <i>World J Stem Cells</i> 2025; 17(10): 112397</p>
URL	https://www.wjgnet.com/1948-0210/full/v17/i10/112397.htm
DOI	https://dx.doi.org/10.4252/wjsc.v17.i10.112397

Full Article (PDF)	WJSC-17-112397-with-cover.pdf
Manuscript File	112397_Auto_Edited_061531.docx
Answering Reviewers	112397-answering-reviewers.pdf
Audio Core Tip	112397-audio.m4a
Conflict-of-Interest Disclosure Form	112397-conflict-of-interest-statement.pdf
Copyright License Agreement	112397-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	112397-non-native-speakers.pdf
Peer-review Report	112397-peer-reviews.pdf
Scientific Misconduct Check	112397-scientific-misconduct-check.png
Scientific Editor Work List	112397-scientific-editor-work-list.pdf
CrossCheck Report	112397-crosscheck-report.pdf