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Articles Published Processes
2/28/2026 8:32:58 AM | Browse: 3 | Download: 0
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Received |
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2025-09-16 09:24 |
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Peer-Review Started |
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2025-09-16 09:24 |
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First Decision by Editorial Office Director |
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2025-10-13 03:08 |
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Return for Revision |
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2025-10-13 03:08 |
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Revised |
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2025-11-13 12:23 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-09 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-10 01:48 |
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Articles in Press |
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2025-12-10 01:48 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-12 09:32 |
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Publish the Manuscript Online |
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2026-02-28 08:32 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychology |
| Manuscript Type |
Case Control Study |
| Article Title |
Serum folate and brain-derived neurotrophic factor in pediatric autism spectrum disorder and their predictive role in illness severity
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li-Bin Chen, Xiao-Qin Xu and Yan-Hui Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fujian Provincial Health Technology Project |
2020QNA012 |
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| Corresponding Author |
Yan-Hui Chen, Professor, Department of Pediatrics, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Gulou District, Fuzhou 350001, Fujian Province, China. deag0225@126.com |
| Key Words |
Serum folate; Brain-derived neurotrophic factor; Autism spectrum disorder; Children; Illness severity; Receiver operating characteristic curve |
| Core Tip |
We selected 53 autism spectrum disorder (ASD)-affected children and 50 healthy controls. Serum folate (SF) was down-regulated and brain-derived neurotrophic factor (BDNF) was up-regulated in ASD children. Both indices related closely to illness severity and could reflect therapeutic effectiveness. Moreover, low SF and high BDNF levels held predictive value for ASD aggravation in children. |
| Publish Date |
2026-02-28 08:32 |
| Citation |
Chen LB, Xu XQ, Chen YH. Serum folate and brain-derived neurotrophic factor in pediatric autism spectrum disorder and their predictive role in illness severity. World J Psychiatry 2026; 16(3): 112418 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i3/112418.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i3.112418 |
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