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Publication Name World Journal of Psychiatry
Manuscript ID 112431
Country China
Received
2025-07-28 05:05
Peer-Review Started
2025-07-28 05:05
To Make the First Decision
Return for Revision
2025-07-31 07:29
Revised
2025-08-09 16:37
Second Decision
2025-09-04 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-04 09:43
Articles in Press
2025-09-04 09:43
Publication Fee Transferred
2025-08-12 05:43
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-21 09:30
Publish the Manuscript Online
2025-11-04 02:41
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Randomized Controlled Trial
Article Title Computerized cognitive behavioral therapy with sertraline in schizophrenia with depressive episodes: A 12-week randomized controlled trial
Manuscript Source Unsolicited Manuscript
All Author List Ren-Chun Huang, Nicha Wareesawetsuwan, Nan Lin and Xiao-Dan Li
ORCID
Author(s) ORCID Number
Xiao-Dan Li http://orcid.org/0009-0007-3492-1296
Funding Agency and Grant Number
Funding Agency Grant Number
Fuzhou Science and Technology Plan Project 2023-S-028
Corresponding Author Xiao-Dan Li, MD, PhD, Department of Psychiatry, The Second General Hospital of Fuzhou Neuropsychiatric Prevention and Treatment Hospital, No. 451, South Second Ring Road, Fuzhou 350004, China. 810538265@qq.com
Key Words Schizophrenia with depressive episode; Computerized cognitive behavioral therapy; Sertraline; Cognitive function; Quality of life; Randomized controlled trial
Core Tip This randomized controlled trial demonstrates that combining computerized cognitive behavioral therapy (CCBT) with sertraline is more effective than sertraline alone in improving depressive symptoms, cognitive function, and quality of life in patients with schizophrenia and depressive episodes. Notably, CCBT significantly enhanced processing speed and social cognition. These findings support CCBT as a scalable, accessible, and effective adjunct to pharmacotherapy in this challenging population.
Publish Date 2025-11-04 02:41
Citation <p>Huang RC, Wareesawetsuwan N, Lin N, Li XD. Computerized cognitive behavioral therapy with sertraline in schizophrenia with depressive episodes: A 12-week randomized controlled trial. <i>World J Psychiatry</i> 2025; 15(11): 112431</p>
URL https://www.wjgnet.com/2220-3206/full/v15/i11/112431.htm
DOI https://dx.doi.org/10.5498/wjp.v15.i11.112431
Full Article (PDF) WJP-15-112431-with-cover.pdf
CONSORT 2010 Statement 112431-CONSORT-2010-statement.pdf
Manuscript File 112431_Auto_Edited_033334.docx
Answering Reviewers 112431-answering-reviewers.pdf
Audio Core Tip 112431-audio.m4a
Biostatistics Review Certificate 112431-biostatistics-statement.pdf
Clinical Trial Registration Statement 112431-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 112431-conflict-of-interest-statement.pdf
Copyright License Agreement 112431-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 112431-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 112431-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 112431-non-native-speakers.pdf
Supplementary Material 112431-supplementary-material.pdf
Peer-review Report 112431-peer-reviews.pdf
Scientific Misconduct Check 112431-scientific-misconduct-check.png
Scientific Editor Work List 112431-scientific-editor-work-list.pdf
CrossCheck Report 112431-crosscheck-report.pdf