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12/23/2025 6:25:18 AM | Browse: 28 | Download: 106
Publication Name World Journal of Clinical Oncology
Manuscript ID 112443
Country Italy
Received
2025-07-28 05:48
Peer-Review Started
2025-07-28 05:48
First Decision by Editorial Office Director
2025-08-20 07:53
Return for Revision
2025-08-20 07:53
Revised
2025-09-01 17:34
Publication Fee Transferred
Second Decision by Editor
2025-11-07 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-07 07:59
Articles in Press
2025-11-07 07:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-10 00:57
Publish the Manuscript Online
2025-12-23 06:25
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Retrospective Cohort Study
Article Title Expanding the role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: A multicenter study on uncommon peritoneal malignancies
Manuscript Source Invited Manuscript
All Author List Massimo Framarini, Fabrizio D'Acapito, Piero Vincenzo Lippolis, Andrea Di Giorgio, Daniela Di Pietrantonio, Antonio Sommariva and Paolo Sammartino
ORCID
Author(s) ORCID Number
Massimo Framarini http://orcid.org/0000-0002-7374-8998
Fabrizio D'Acapito http://orcid.org/0000-0001-6420-6209
Piero Vincenzo Lippolis http://orcid.org/0009-0009-7424-4335
Andrea Di Giorgio http://orcid.org/0000-0003-3981-1145
Daniela Di Pietrantonio http://orcid.org/0000-0002-1276-2382
Antonio Sommariva http://orcid.org/0000-0002-5764-5606
Paolo Sammartino http://orcid.org/0000-0002-5513-6349
Funding Agency and Grant Number
Corresponding Author Fabrizio D'Acapito, Consultant, PhD, General and Oncologic Surgery, Morgagni-Pierantoni Hospital, AUSL Romagna, via Carlo Forlanini 34, Forli 47121, Emilia-Romagna, Italy. fabrizioda@gmail.com
Key Words Cytoreductive surgery; Hyperthermic intraperitoneal chemotherapy; Uncommon peritoneal malignancies; Peritoneal surface malignancy; Oncologic outcomes
Core Tip This multicenter retrospective study evaluates the safety and efficacy of cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal metastases (PM) from uncommon primary tumors. Among 60 patients treated across five high-volume centers, long-term survival was observed in selected cases, particularly those with breast or uterine cancer. Tumor origin emerged as the strongest independent predictor of overall survival, whereas timing of PM (synchronous vs metachronous) showed a variable prognostic impact. These findings support CRS + HIPEC as a potentially valuable option in rare indications when patients are carefully selected.
Publish Date 2025-12-23 06:25
Citation

Framarini M, D'Acapito F, Lippolis PV, Di Giorgio A, Di Pietrantonio D, Sommariva A, Sammartino P. Expanding the role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: A multicenter study on uncommon peritoneal malignancies. World J Clin Oncol 2025; 16(12): 112443

URL https://www.wjgnet.com/2218-4333/full/v16/i12/112443.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i12.112443
Full Article (PDF) WJCO-16-112443-with-cover.pdf
STROBE Statement 112443-STROBE-statement.pdf
Manuscript File 112443_Auto_Edited_013638.docx
Answering Reviewers 112443-answering-reviewers.pdf
Audio Core Tip 112443-audio.mp3
Biostatistics Review Certificate 112443-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 112443-conflict-of-interest-statement.pdf
Copyright License Agreement 112443-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 112443-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 112443-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 112443-non-native-speakers.pdf
Peer-review Report 112443-peer-reviews.pdf
Scientific Misconduct Check 112443-scientific-misconduct-check.png
Scientific Editor Work List 112443-scientific-editor-work-list.pdf
CrossCheck Report 112443-crosscheck-report.pdf