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Articles Published Processes
12/31/2025 5:47:38 AM | Browse: 1 | Download: 1
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Received |
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2025-07-28 02:41 |
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Peer-Review Started |
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2025-07-28 02:41 |
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First Decision by Editorial Office Director |
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2025-09-02 02:06 |
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Return for Revision |
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2025-09-02 02:06 |
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Revised |
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2025-09-12 10:34 |
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Publication Fee Transferred |
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2025-09-13 06:41 |
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Second Decision by Editor |
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2025-10-22 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-22 08:04 |
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Articles in Press |
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2025-10-22 08:04 |
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Edit the Manuscript by Language Editor |
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2025-10-23 02:15 |
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Typeset the Manuscript |
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2025-12-19 02:40 |
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Publish the Manuscript Online |
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2025-12-31 05:47 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Preoperative butyrylcholinesterase activity and risk of postoperative delirium: A meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yuan-Li Qiu, Cheng Song, Cui-Wan Huang and Wei-Gang Shen |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wei-Gang Shen, Director, Department of Anesthesiology, Affiliated Hospital of Shaoxing University, No. 999, Zhongxing South Road, Chengnan Sub-district, Yuecheng District, Shaoxing 312000, Zhejiang Province, China. 313693178@qq.com |
| Key Words |
Acetylcholinesterase; Butyrylcholinesterase; Activity; Postoperative delirium; Meta-analysis |
| Core Tip |
This meta-analysis synthesizes evidence from 13 studies involving 2730 surgical patients to assess the association between preoperative cholinesterase activity and postoperative delirium (POD). We found that lower preoperative butyrylcholinesterase (BuChE) activity was significantly associated with increased POD risk, whereas acetylcholinesterase activity showed no consistent association. These findings suggest that serum BuChE may serve as a simple, accessible biomarker for POD risk stratification. Our study provides the most comprehensive evidence to date linking peripheral cholinergic dysfunction to POD and highlights BuChE as a potential target for early identification and intervention. |
| Publish Date |
2025-12-31 05:47 |
| Citation |
Qiu YL, Song C, Huang CW, Shen WG. Preoperative butyrylcholinesterase activity and risk of postoperative delirium: A meta-analysis. World J Psychiatry 2026; 16(1): 112450 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i1/112450.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i1.112450 |
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