| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Retrospective Study |
| Article Title |
Clinical predictors of multidrug-resistant Gram-negative pyogenic liver abscess and nomogram construction: A retrospective analysis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ke Xu, Dong-Hui Wu, Chu-Jia Zeng, Jia-Yi Guo, De-Yang Xi, Meng-Jiao Wang, Zhi-Yuan Yao, An-Qiang Feng, Fang Ji, Xue-Bing Yan, Li-Li Ye and Chun-Yang Li |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Chun-Yang Li, Chief Physician, Department of Infectious Diseases, The Affiliated Hospital of Xuzhou Medical University, No. 9 Kunpeng North Road, Economic and Technological Development Zone, Xuzhou 221132, Jiangsu Province, China. lichunyangyelili@126.com |
| Key Words |
Pyogenic liver abscess; Multidrug-resistant bacterial infection; Gram-negative bacteria; Predictive model; Clinical features |
| Core Tip |
This study identifies age ≥ 60, diabetes, malignant tumor, lower C-reactive protein levels, and prolonged prothrombin time as independent predictors of multidrug-resistant Gram-negative bacteria pyogenic liver abscess, primarily caused by Klebsiella pneumoniae and Escherichia coli. A validated nomogram incorporating these factors enables personalized risk assessment, facilitating early screening and optimized empirical antibiotic therapy for enhanced clinical outcomes. Findings are based on retrospective analysis of 268 Gram-negative pyogenic liver abscess cases. |
| Publish Date |
2025-11-13 06:51 |
| Citation |
Xu K, Wu DH, Zeng CJ, Guo JY, Xi DY, Wang MJ, Yao ZY, Feng AQ, Ji F, Yan XB, Ye LL, Li CY. Clinical predictors of multidrug-resistant Gram-negative pyogenic liver abscess and nomogram construction: A retrospective analysis. World J Gastroenterol 2025; 31(42): 112478 |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i42/112478.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i42.112478 |
