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1/5/2026 3:46:21 AM | Browse: 4 | Download: 25
Publication Name World Journal of Gastroenterology
Manuscript ID 112496
Country India
Received
2025-07-28 14:22
Peer-Review Started
2025-07-28 14:22
First Decision by Editorial Office Director
2025-08-27 09:17
Return for Revision
2025-08-27 09:17
Revised
2025-09-09 15:09
Publication Fee Transferred
Second Decision by Editor
2025-11-11 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-11 07:33
Articles in Press
2025-11-11 07:33
Edit the Manuscript by Language Editor
2025-11-14 20:55
Typeset the Manuscript
2025-12-25 11:25
Publish the Manuscript Online
2026-01-05 03:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Gene, genetics and genetic medicines in gastroenterology: Current status and its future
Manuscript Source Invited Manuscript
All Author List Ashok Kumar, Yajnadatta Sarangi and Payal Kaw
ORCID
Author(s) ORCID Number
Ashok Kumar http://orcid.org/0000-0003-3959-075X
Yajnadatta Sarangi http://orcid.org/0000-0003-4951-6705
Payal Kaw http://orcid.org/0000-0001-7203-2341
Funding Agency and Grant Number
Corresponding Author Ashok Kumar, FACS, FASCRS, FRCS, FRCS (Ed), Full Professor, Professor, Department of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, Uttar Pradesh, India. doc.ashokgupta@gmail.com
Key Words Genes; Genetics; Clinical genetic testing; Germline mutation; Somatic mutation; Targeted therapy; Pharmacogenetics; Genetic medicine; Gastroenterology; Gastrointestinal diseases
Core Tip With advancements in genetics, there are emerging trends in better understanding of diseases and diagnose many undiagnosed gastrointestinal disorders and search for newer medicines which are pivotal to the progress of precision medicine. Genetic analysis enables accurate diagnosis, risk stratification, and individualized treatment by identifying germline mutations, somatic alterations, and epigenetic changes. It also plays a crucial role in predicting treatment response and guiding targeted therapies. Gene therapy, gene editing, and clustered regularly interspaced short palindromic repeats-clustered regularly interspaced short palindromic repeat-associated protein systems represent promising tools for managing, many complex gastrointestinal disorders and also an aid to the conventional treatment and has very promising future.
Publish Date 2026-01-05 03:46
Citation

Kumar A, Sarangi Y, Kaw P. Gene, genetics and genetic medicines in gastroenterology: Current status and its future. World J Gastroenterol 2026; 32(1): 112496

URL https://www.wjgnet.com/1007-9327/full/v32/i1/112496.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i1.112496
Full Article (PDF) WJG-32-112496-with-cover.pdf
Manuscript File 112496_Auto_Edited_025529.docx
Answering Reviewers 112496-answering-reviewers.pdf
Audio Core Tip 112496-audio.mp3
Conflict-of-Interest Disclosure Form 112496-conflict-of-interest-statement.pdf
Copyright License Agreement 112496-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 112496-non-native-speakers.pdf
Peer-review Report 112496-peer-reviews.pdf
Scientific Misconduct Check 112496-scientific-misconduct-check.png
Scientific Editor Work List 112496-scientific-editor-work-list.pdf
CrossCheck Report 112496-crosscheck-report.pdf