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Articles Published Processes
1/5/2026 3:46:21 AM | Browse: 4 | Download: 25
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Received |
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2025-07-28 14:22 |
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Peer-Review Started |
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2025-07-28 14:22 |
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First Decision by Editorial Office Director |
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2025-08-27 09:17 |
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Return for Revision |
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2025-08-27 09:17 |
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Revised |
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2025-09-09 15:09 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-11 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-11 07:33 |
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Articles in Press |
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2025-11-11 07:33 |
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Edit the Manuscript by Language Editor |
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2025-11-14 20:55 |
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Typeset the Manuscript |
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2025-12-25 11:25 |
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Publish the Manuscript Online |
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2026-01-05 03:46 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Gene, genetics and genetic medicines in gastroenterology: Current status and its future
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ashok Kumar, Yajnadatta Sarangi and Payal Kaw |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ashok Kumar, FACS, FASCRS, FRCS, FRCS (Ed), Full Professor, Professor, Department of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, Uttar Pradesh, India. doc.ashokgupta@gmail.com |
| Key Words |
Genes; Genetics; Clinical genetic testing; Germline mutation; Somatic mutation; Targeted therapy; Pharmacogenetics; Genetic medicine; Gastroenterology; Gastrointestinal diseases |
| Core Tip |
With advancements in genetics, there are emerging trends in better understanding of diseases and diagnose many undiagnosed gastrointestinal disorders and search for newer medicines which are pivotal to the progress of precision medicine. Genetic analysis enables accurate diagnosis, risk stratification, and individualized treatment by identifying germline mutations, somatic alterations, and epigenetic changes. It also plays a crucial role in predicting treatment response and guiding targeted therapies. Gene therapy, gene editing, and clustered regularly interspaced short palindromic repeats-clustered regularly interspaced short palindromic repeat-associated protein systems represent promising tools for managing, many complex gastrointestinal disorders and also an aid to the conventional treatment and has very promising future. |
| Publish Date |
2026-01-05 03:46 |
| Citation |
Kumar A, Sarangi Y, Kaw P. Gene, genetics and genetic medicines in gastroenterology: Current status and its future. World J Gastroenterol 2026; 32(1): 112496 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i1/112496.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i1.112496 |
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