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12/25/2025 8:27:23 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 112520
Country China
Received
2025-07-31 02:33
Peer-Review Started
2025-07-31 02:33
First Decision by Editorial Office Director
2025-09-17 08:36
Return for Revision
2025-09-17 08:45
Revised
2025-09-26 20:16
Publication Fee Transferred
Second Decision by Editor
2025-10-27 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-27 10:03
Articles in Press
2025-10-27 10:03
Edit the Manuscript by Language Editor
2025-11-02 20:10
Typeset the Manuscript
2025-12-15 02:32
Publish the Manuscript Online
2025-12-25 08:27
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Retrospective Study
Article Title Machine-learning-based prediction model for Clavien-Dindo grade ≥ II complications after neoadjuvant therapy and laparoscopic gastrectomy in gastric cancer
Manuscript Source Invited Manuscript
All Author List Ru-Yin Li, Zi-Rui Zhao, Tian Yu and Jian-Chun Yu
ORCID
Author(s) ORCID Number
Ru-Yin Li http://orcid.org/0000-0001-8733-3235
Jian-Chun Yu http://orcid.org/0000-0002-9342-8828
Funding Agency and Grant Number
Funding Agency Grant Number
National Key Research and Development Program of China 2022YFF1100404
National High Level Hospital Clinical Research Funding of China 2022-PUMCH-B-005
Corresponding Author Jian-Chun Yu, Chief, MD, PhD, Professor, Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100730, China. yu-jch@163.com
Key Words Gastric cancer; Machine learning; Postoperative complications; Risk prediction; Neoadjuvant therapy
Core Tip Addressing data scarcity in gastric cancer neoadjuvant therapy, this study used a large patient cohort (n = 455) to pioneer a machine learning model for predicting Clavien-Dindo grade ≥ II complications post-neoadjuvant therapy and laparoscopic gastrectomy. Key predictors included smoking status, Nutritional Risk Screening-2002 score, American Society of Anesthesiologists classification, neoadjuvant therapy, surgical approach, operating time, and intraoperative blood loss. The neural network ensemble model demonstrated superior performance, with optimal discrimination, calibration, and clinical utility, potentially offering a tool for perioperative risk stratification and management optimization.
Publish Date 2025-12-25 08:27
Citation

Li RY, Zhao ZR, Yu T, Yu JC. Machine-learning-based prediction model for Clavien-Dindo grade ≥ II complications after neoadjuvant therapy and laparoscopic gastrectomy in gastric cancer. World J Gastrointest Surg 2025; 17(12): 112520

URL https://www.wjgnet.com/1948-9366/full/v17/i12/112520.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i12.112520
Full Article (PDF) WJGS-17-112520-with-cover.pdf
Manuscript File 112520_Auto_Edited_011236.docx
Answering Reviewers 112520-answering-reviewers.pdf
Audio Core Tip 112520-audio.mp3
Biostatistics Review Certificate 112520-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 112520-conflict-of-interest-statement.pdf
Copyright License Agreement 112520-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 112520-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 112520-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 112520-non-native-speakers.pdf
Supplementary Material 112520-supplementary-material.pdf
Peer-review Report 112520-peer-reviews.pdf
Scientific Misconduct Check 112520-scientific-misconduct-check.png
Scientific Editor Work List 112520-scientific-editor-work-list.pdf
CrossCheck Report 112520-crosscheck-report.pdf