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Articles Published Processes
12/10/2025 7:48:08 AM | Browse: 2 | Download: 1
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Received |
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2025-07-30 14:13 |
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Peer-Review Started |
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2025-07-30 14:13 |
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First Decision by Editorial Office Director |
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2025-08-27 09:23 |
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Return for Revision |
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2025-08-27 09:23 |
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Revised |
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2025-09-23 21:28 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-23 02:31 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-23 06:59 |
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Articles in Press |
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2025-10-23 06:59 |
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Edit the Manuscript by Language Editor |
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2025-10-31 11:44 |
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Typeset the Manuscript |
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2025-12-04 07:38 |
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Publish the Manuscript Online |
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2025-12-10 07:48 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Clinical utility of telomeres as diagnostic and short-term prognostic markers in loco-regional treatment of hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sarah El-Nakeep, Hossameldin AbdelAziz, Tari George Michael, Ahmed Mohamed ElGhandour, Hoda A Abdelsattar, Fatma Mohamed Rafat Awad and Anup Kasi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sarah El-Nakeep, MD, Professor, Hepatogastroenterology Unit, Internal Medicine Department, Faculty of Medicine, Ain Shams University, Ramsses street, Abassyia Square, Cairo 11736, Egypt. sarahnakeep@gmail.com |
| Key Words |
Hepatocellular carcinoma; Telomeres; Telomere length; Telomerase; Transarterial chemoembolization; Radiofrequency; Locoregional therapy; Diagnosis; Prognosis |
| Core Tip |
We examined the telomere length in peripheral leucocytes, as a biomarker for diagnosis and short-term prognosis for locoregional therapy of hepatocellular carcinoma (HCC). We found that in patients with HCC or chronic liver disease, the telomere length is short. When we used a cutoff of 5 cm we found that in patients with larger tumors, the telomere length is shorter. Moreover, in large tumors the telomere length increases, as the size of the tumor increases. Ours is the first study on Egyptian patients. We hope this study paves the way for further research on telomeres in HCC prognosis, and diagnosis. |
| Publish Date |
2025-12-10 07:48 |
| Citation |
El-Nakeep S, AbdelAziz H, Michael TG, ElGhandour AM, Abdelsattar HA, Awad FMR, Kasi A. Clinical utility of telomeres as diagnostic and short-term prognostic markers in loco-regional treatment of hepatocellular carcinoma. World J Gastroenterol 2025; 31(46): 112530 |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i46/112530.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i46.112530 |
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